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ChemicalBook >> CAS DataBase List >> SC 57461A

SC 57461A

SC 57461A price.
  • $32 - $2240.7
  • Product name: SC 57461A
  • CAS: 423169-68-0
  • MF: C20H25NO3.ClH
  • MW: 363.882
  • EINECS:
  • MDL Number:MFCD00951253
  • Synonyms:SC-57461 Hydrochloride;SC 57461A;N-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-β-alaninehydrochloride;SC 57461;inhibit,SC57461A,SC 57461A,Leukotriene A4,SC-57461A,Inhibitor,Aminopeptidase,orally active,LTA4 hydrolase;3-((3-(4-Benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride
19 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3673BB
  • Product description3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3673BB
  • Product description3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid
  • Packaging10mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010337
  • Product descriptionN-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$785.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010337
  • Product descriptionN-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$2240.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4408
  • Product descriptionSC57461A
  • Packaging50mg
  • Price$1078
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10108
  • Product descriptionSC-57461A ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10108
  • Product descriptionSC-57461A ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10108
  • Product descriptionSC-57461A ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10108
  • Product descriptionSC-57461A ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23005
  • Product descriptionSC57461 >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23005
  • Product descriptionSC57461 >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23005
  • Product descriptionSC57461 >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0110
  • Product descriptionSC-57461A ≥98% (HPLC)
  • Packaging25mg
  • Price$461
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0110
  • Product descriptionSC-57461A ≥98% (HPLC)
  • Packaging5mg
  • Price$147
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3107
  • Product descriptionSC57461A ≥98%(HPLC)
  • Packaging10
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3107
  • Product descriptionSC57461A ≥98%(HPLC)
  • Packaging50
  • Price$548
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3673BB 3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid 1mg $133 2021-12-16 Buy
AK Scientific 3673BB 3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid 10mg $286 2021-12-16 Buy
American Custom Chemicals Corporation API0010337 N-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00% 10MG $785.4 2021-12-16 Buy
American Custom Chemicals Corporation API0010337 N-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00% 100MG $2240.7 2021-12-16 Buy
ApexBio Technology A4408 SC57461A 50mg $1078 2021-12-16 Buy
Cayman Chemical 10108 SC-57461A ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 10108 SC-57461A ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 10108 SC-57461A ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 10108 SC-57461A ≥98% 25mg $381 2024-03-01 Buy
DC Chemicals DC23005 SC57461 >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC23005 SC57461 >98% 250mg $950 2021-12-16 Buy
DC Chemicals DC23005 SC57461 >98% 1g $1900 2021-12-16 Buy
Sigma-Aldrich PZ0110 SC-57461A ≥98% (HPLC) 25mg $461 2024-03-01 Buy
Sigma-Aldrich PZ0110 SC-57461A ≥98% (HPLC) 5mg $147 2024-03-01 Buy
Tocris 3107 SC57461A ≥98%(HPLC) 10 $128 2021-12-16 Buy
Tocris 3107 SC57461A ≥98%(HPLC) 50 $548 2021-12-16 Buy

Properties

Melting point :163-165°C
storage temp. :Desiccate at +4°C
solubility :DMSO: >5mg/mL
form :powder
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in whole blood (IC50 = 49 nM). It blocks both the hydrolase and aminopeptidase activity in vitro. SC-57461A is without effect against other enzymes of the arachidonic acid cascade, including 5-lipoxygenase, LTC4 synthase, COX-1, and COX-2. In a rat model of ionophore-induced peritoneal eicosanoid production, SC-57461A inhibits LTB4 biosynthesis without affecting LTC4 or 6-keto prostaglandin F1α production . Oral or topical pretreatment with SC-57461A before challenge with arachidonic acid blocks ear edema in mice.

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