Entecavir hydrate
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- CAS-Nr.
- 209216-23-9
- Englisch Name:
- Entecavir hydrate
- Synonyma:
- CS-130;cGMP Entecavir;ecavir hydrate;SET in house/USP;Enticavir hydrate;entecavir hydrate;Entecavir one water;ENTECAVIR MONOHYDRATE;Enteeavir Monohydrate;Entecavir momohydrate
- CBNumber:
- CB9854927
- Summenformel:
- C12H17N5O4
- Molgewicht:
- 295.3
- MOL-Datei:
- 209216-23-9.mol
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Entecavir hydrate Eigenschaften
- Schmelzpunkt:
- >220°
- alpha
- D +35.0° (c = 0.38 in water)
- Dichte
- 1.81
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- DMSO (Slightly), Methanol (Sparingly), Water (Slightly, Heated, Sonicated)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Merck
- 14,3595
- InChI
- InChI=1/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/s3
- InChIKey
- YXPVEXCTPGULBZ-UQHDSAJHNA-N
- SMILES
- C=C1[C@@H]([C@@H](O)C[C@@H]1N1C=NC2C(NC(N)=NC1=2)=O)CO.O |&1:2,3,6,r|
- CAS Datenbank
- 209216-23-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| HS Code |
29339900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
| H372 |
Sch?digt bei Hautkontakt und Verschlucken die Organe bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P260, P264, P270, P314, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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Entecavir hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Entecavir hydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the vira
Definition
ChEBI: Entecavir hydrate is the monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug. It contains an entecavir (anhydrous).
Trademarks
Baraclude (Bristol-Myers Squibb).
Entecavir hydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Entecavir hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 494)Lieferanten
209216-23-9()Verwandte Suche:
- entecavir hydrate
- ENTECAVIR MONOHYDRATE
- 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate
- Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate
- 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.9%
- 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.7%
- Entecavir Monohydrate IsoMers
- 2-aMino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxyMethyl)-2-Methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one
- Entecavir hydrate /entecavir
- 2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purin-6(9H)-one hydrate
- Enticavir hydrate
- Entecavir Monohydrate (200 mg)
- Entecavir monohydrate, >=99%
- cGMP Entecavir
- Benzoic acid, 3-methyl-4-[(1-oxobutyl)amino]-, methyl ester
- 2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purin-6(9H)-one h
- Entecavir (with water)
- Entecavir monohydrate and intermediates
- Entecavir hydrate, 97%, a nucleoside analog that inhibits reverse transcription
- SET in house/USP
- CS-130
- Entecavir monohydrate (BMS200475 monohydrate)
- ETV;BARACLUDE;SQ 34676;BMS 200475;SQ34676;BMS200475;SQ-34676;BMS-200475
- EntecavirMonohydrate>
- Entecavir monohydrate CRS
- Entecavir for system suitability CRS
- 9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine
- Entecavir hydrate USP/EP/BP
- Entecavir Monohydrate (API)
- Entecavir hydrate,Entecavir monohydrate
- Entecavir Hydrate (BMS200475)
- US-DMF No.: 031949
CEP No.: 2018-283
- Entecavir MonohydrateQ: What is
Entecavir Monohydrate Q: What is the CAS Number of
Entecavir Monohydrate Q: What is the storage condition of
Entecavir Monohydrate Q: What are the applications of
Entecavir Monohydrate
- ecavir hydrate
- Entecavir Monohydrate (1235966)
- 2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one hydrate
- Entecavir hydrate monohydrate AKSci P238
- 20β-carboxyaldehyde-4-pregnen-3-one
- Entecavir Monohydrate USP/IP/PH.Eur
- Entecavir one water
- Enteeavir Monohydrate
- Entecavir momohydrate
- Entecavir monohydrate, 10 mM in DMSO
- 209216-23-9
- C12H15N5O3H2O
- Liver Disease Series
- Baraclude
- API
- 209216-23-9
