Flibanserin
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- CAS-Nr.
- 167933-07-5
- Englisch Name:
- Flibanserin
- Synonyma:
- Filbanserin;Flibanserine;BIMT;Niemunerkeine;1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one;Girosa;Bimt 17;BIMT 17BS;Fbanselin;Flibanerins
- CBNumber:
- CB91178756
- Summenformel:
- C20H21F3N4O
- Molgewicht:
- 390.4
- MOL-Datei:
- 167933-07-5.mol
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Flibanserin Eigenschaften
- Dichte
- 1.292±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble10mg/mL, clear
- Aggregatzustand
- powder
- pka
- 12.12±0.30(Predicted)
- Farbe
- white to beige
- InChI
- InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28)
- InChIKey
- PPRRDFIXUUSXRA-UHFFFAOYSA-N
- SMILES
- C1(=O)N(CCN2CCN(C3=CC=CC(C(F)(F)F)=C3)CC2)C2=CC=CC=C2N1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
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| Sicherheit |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Flibanserin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Flibanserin is a drug originally
developed by Boehringer-Ingelheim and later Sprout Pharmaceuticals, which was approved in 2015 by the FDA for the
treatment of premenopausal women with hypoactive sexual
desire disorder (HSDD). The drug, which was originally
developed for the treatment of depression by Boehringer-
Ingelheim, is a full agonist of the 5-HT1A receptor, an
antagonist of the 5-HT2A receptor, and a partial agonist of
the dopamine-4 (D4) receptor, which triggers increased
dopamine and norepinephrine levels along with decreased
serotonin levels. In three randomized trials
involving 2400 premenopausal women, the drug was found
to increase the number of satisfying sexual events by 0.5-1.0
events per month and increased sexual desire on average by
10-12% over placebo. Side effects include decreased blood
pressure and loss of consciousness, especially in subjects who
consumed alcohol.
Verwenden
Antidepressant (5-HT1a agonist and 5-HT2 antagonist).
Flibanserin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Flibanserin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 346)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Baoji Guokang Bio-Technology Co., Ltd.
|
0917-3909592 13892490616
|
gksales1@gk-bio.com |
China |
9315 |
58 |
|
Guangzhou TongYi biochemistry technology Co.,LTD
|
+8613073028829
|
mack@tongyon.com |
China |
2994 |
58 |
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Wuhan Mayue Longteng Technology Development Co., Ltd.
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+undefined15171477138
|
helen.yan@lantu-tech.com |
China |
293 |
58 |
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hebei hongtan Biotechnology Co., Ltd
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+86-86-1913198-3935 +8617331935328
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sales03@chemcn.cn |
China |
970 |
58 |
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Apeloa production Co.,Limited
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+8619933239880
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admin@apcl.com.cn |
China |
852 |
58 |
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Hebei Mojin Biotechnology Co., Ltd
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+86 13288715578 +8613288715578
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sales@hbmojin.com |
China |
12825 |
58 |
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Hebei Chuanghai Biotechnology Co,.LTD
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+86-13131129325
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sales1@chuanghaibio.com |
China |
5893 |
58 |
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Firsky International Trade (Wuhan) Co., Ltd
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+8615387054039
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admin@firsky-cn.com |
China |
427 |
58 |
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Anhui Ruihan Technology Co., Ltd
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+8617756083858
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daisy@anhuiruihan.com |
China |
973 |
58 |
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Wuhan Quanjinci New Material Co.,Ltd.
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+86-15271838296; +8615271838296
|
kyra@quanjinci.com |
China |
1512 |
58 |
167933-07-5()Verwandte Suche:
- Flibanserin,Bimt 17, Bimt-17-BS,Girosa
- Flibanserin
- Bimt 17
- 3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
- Flibanerins
- BIMT 17BS
- 2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-
- Flibanserin(BIMT17)
- 3-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-1H-benzimidazol-2-one
- Flibaneserin
- BIMT-17;BIMT-17BS
- Flubensin (female)
- Flibaserin(female)
- Fbanselin
- Flubanserin
- crystal paracetamol Flibanserin CAS NO.167933-07-5
- Girosa
- Color Lin fluorine class
- Flibanserin USP/EP/BP
- Flibaserin USP/EP/BP
- 2-Flibanserin
- Flibanserin ADDYI
- Flibanserin powder
- Filbanserin
- 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
- Niemunerkeine
- Flibanserine
- BIMT
- 1-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one
- 167933-07-5
- C20H21F3N4O
- API
- API,chemical material
