Propylencarbonat
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Propylencarbonat Eigenschaften
- Schmelzpunkt:
- -55 °C (lit.)
- Siedepunkt:
- 240 °C (lit.)
- Dichte
- 1.204 g/mL at 25 °C (lit.)
- Dampfdruck
- 0.13 mm Hg ( 20 °C)
- Brechungsindex
- n
20/D 1.421(lit.)
- Flammpunkt:
- 270 °F
- storage temp.
- Store below +30°C.
- L?slichkeit
- 240g/l
- Aggregatzustand
- Liquid
- pka
- 3.92[at 20 ℃]
- Farbe
- Clear
- Wichte
- 1.209 (20/4℃)
- Relative polarity
- 6
- PH
- 7.0 (200g/l, H2O, 20℃)
- Geruch (Odor)
- odorless
- Explosionsgrenze
- 1.8-14.3%(V)
- Wasserl?slichkeit
- 240 g/L (20 ºC)
- maximale Wellenl?nge (λmax)
- λ: 235 nm Amax: 1.00
λ: 280 nm Amax: 0.50
λ: 300 nm Amax: 0.30
λ: 350 nm Amax: 0.05
λ: 375-400 nm Amax: 0.01
- BRN
- 107913
- Dielectric constant
- 64.4(Ambient)
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents, acids, bases, reducing agents. Protect from contact with moist air or water.
- InChIKey
- RUOJZAUFBMNUDX-UHFFFAOYSA-N
- LogP
- -0.41 at 20℃
- CAS Datenbank
- 108-32-7(CAS DataBase Reference)
- NIST chemische Informationen
- Propylene carbonate(108-32-7)
- EPA chemische Informationen
- Propylene carbonate (108-32-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xi | ||
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R-S?tze: | 36 | ||
S-S?tze: | 26-37/39 | ||
WGK Germany | 1 | ||
RTECS-Nr. | FF9650000 | ||
F | 3-10 | ||
Selbstentzündungstemperatur | 851 °F | ||
TSCA | Yes | ||
HS Code | 29209010 | ||
Giftige Stoffe Daten | 108-32-7(Hazardous Substances Data) | ||
Toxizit?t | LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 20000 mg/kg |
Bildanzeige (GHS) |
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Sicherheit |
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Propylencarbonat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36:Reizt die Augen.S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Propylene carbonate is a clear, colorless, mobile liquid, with a faint odor.Verwenden
propylene carbonate is used in chemical reactions as a solvent, plasticizer, solubilizer, or dilutent. It is also used in the synthesis of solar cells as well as lithium ion batteries.Vorbereitung Methode
Propylene carbonate may be prepared by the reaction of sodium bicarbonate with propylene chlorohydrin.Allgemeine Beschreibung
Propylene carbonate is a cyclic carbonate that is commonly used as a solvent and as a reactive intermediate in organic synthesis. It is being considered as a potential electrochemical solvent due to its low vapor pressure, high dielectric constant and high chemical stability.Propylene carbonate can be synthesized from propylene oxide and CO2. Optically active form of propylene carbonate can be prepared from the reaction between CO2 and racemic epoxides. Decomposition of propylene carbonate on the graphite electrode in lithium batteries results in the formation of a lithium intercalated compound.
Pharmazeutische Anwendungen
Propylene carbonate is used mainly as a solvent in oral and topical pharmaceutical formulations.In topical applications, propylene carbonate has been used in combination with propylene glycol as a solvent for corticosteroids. The corticosteroid is dissolved in the solvent mixture to yield microdroplets that can then be dispersed in petrolatum.Propylene carbonate has been used as a dispensing solvent in topical preparations.
Propylene carbonate has also been used in hard gelatin capsules as a nonvolatile, stabilizing, liquid carrier. For formulations with a low dosage of active drug, a uniform drug content may be obtained by dissolving the drug in propylene carbonate and then spraying this solution on to a solid carrier such as compressible sugar; the sugar may then be filled into hard gelatin capsules
Propylene carbonate may additionally be used as a solvent, at room and elevated temperatures, for many cellulose-based polymers and plasticizers. Propylene carbonate is also used in cosmetics.
Sicherheit(Safety)
Propylene Carbonate is listed in The Design for the Environment (DfE) Safer Chemistry Program by the EPA as a Solvent category and indicated by the Green circle, meaning the chemical has been verified to be of low concern for human and environmental health based on experimental and modeled data.In animal studies, propylene carbonate was found to cause tissue necrosis after parenteral administration.
(mouse, oral): 20.7 g/kg
(mouse, SC): 15.8 g/kg
(rat, oral): 29 g/kg
(rat, SC): 11.1 g/kg
Lager
Propylene carbonate and its aqueous solutions are stable but may degrade in the presence of acids or bases, or upon heating;Store in a well-closed container in a cool, dry place.
l?uterung methode
It is manufactured by reaction of 1,2-propylene oxide with CO2 in the presence of a catalyst (quaternary ammonium halide). Contaminants include propylene oxide, carbon dioxide, 1,2-and 1,3-propanediols, allyl alcohol and ethylene carbonate. It can be purified by percolation through molecular sieves (Linde 5A, dried at 350o for 14hours under a stream of argon), followed by distillation under a vacuum. [Jasinski & Kirkland Anal Chem 39 163 1967.] It can be stored over molecular sieves under an inert gas atmosphere. When purified in this way it contains less than 2ppm of water. Activated alumina and dried CaO have also been used as drying agents prior to fractional distillation under reduced pressure. It has been dried with 3A molecular sieves and distilled under nitrogen in the presence of p-toluenesulfonic acid, then redistilled and the middle fraction collected. [Beilstein 19 III/IV 1564, 19/4 V 21.]Inkompatibilit?ten
Propylene carbonate hydrolyzes rapidly in the presence of strong acids and bases, forming mainly propylene oxide and carbon dioxide. Propylene carbonate can also react with primary and secondary amines to yield carbamates.Regulatory Status
Included in the FDA Inactive Ingredients Database (topical ointments). Included in the Canadian List of Acceptable Nonmedicinal Ingredients.Propylencarbonat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
3-Chlorpropan-1-ol
(+)-MENTHYL CHLOROFORMATE
Propan-1,2-diol
1,2-Epoxypropan
MONOMETHYL CARBONATE SODIUM SALT
2-(2-Hydroxypropoxy)propanol
Kohlenstoffdioxid
Downstream Produkte
Propylencarbonat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 706)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
ShanDong Look Chemical Co.,Ltd. | +8617653113219 |
sales01@sdlookchemical.com | China | 2737 | 58 |
ZHEJIANG ESTCHEM CO.,LTD | 15957180504 |
sales@zjestchem.com | China | 193 | 58 |
Taixing Foreign Trade Nanjing Co., Ltd. | +86-025-83346564; +8613182976929 |
sales@tx-chem.com | China | 122 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 12272 | 58 |
Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 |
info@deshangchem.com | China | 662 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8804 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12825 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5887 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 973 | 58 |
108-32-7(Propylencarbonat)Verwandte Suche:
Allylacetat
Methylacetat
PROPYLENE
2-[[[[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid methyl ester
1,3,2-Dioxathian-2-oxid
Calciumcarbonat
Thiophanat-methyl
Dimethylcarbonat
Natriumcarbonat
Tribenuron methyl
Methylsalicylat
Diallylphthalat
1,2-Epoxypropan
Kresoxim-methyl
Propan-1,2-diol
Methyl
PROPYLENE GLYCOL
Diphenylcarbonat
- 1,2-propanediylcarbonate
- 1,3-dioxolane-2-one,4-methyl
- 1-Methylethylene carbonate
- 1-methylethylenecarbonate
- 2-Propanediolcycliccarbonate
- 3-Dioxolan-2-one,4-methyl-1
- 4-methyl-1,3-dioxolan-z-one
- 4-methyl-3-dioxolan-2-one
- 4-Methyldioxalone-2
- Arconate propylene carbonate
- arconate5000
- carbonatedepropylene
- carbonicacid,cyclicpropyleneether
- carbonicacid,propyleneester
- carbonicacidcyclicmethylethyleneester
- Cyclic 1,2-propylene carbonate
- Cyclic methylethylene carbonate
- cyclic1,2-propylenecarbonate
- cyclicmethylethylenecarbonate
- cyclicpropylenecarbonate
- Dipropylene carbonate
- dipropylenecarbonate
- Propylene glycol cyclic carbonate
- propyleneglycolcycliccarbonate
- Propylenester kyseliny uhlicite
- PROPANEDIOL CYCLIC CARBONATE
- PROPYLENE CARBONATE
- PROPYLENE CARBONATE S
- PROPYLENE GLYCOL CARBONATE
- propylene carbonate B&J brand 1 L
- Propylene carhonate
- PROPYLENE CARBONATE, ANHYDROUS
- PROPYLENE CARBONATE, REAGENTPLUS, 99%
- PROPYLENE CARBONATE, ANHYDROUS, 99.7%
- PROPYLENE CARBONATE 99+%
- PROPYLENE CARBONATE, 99.7%, HPLC GRADE
- PROPYLENE CARBONATE 'B&J BRAND'
- Propylene Carbonate, High Purity
- PROPYLENE CARBONATE GC STANDARD
- PropyleneCarbonate(Pc)
- PROPYLENE CARBONATE PESTANAL
- Propylene carbonate, 99.50%
- PROPYLENECARBONATE,REAGENT
- 1,2-Propanediol cyclic carbonate, 4-Methyl-1,3-dioxolan-2-one
- Carbonic acid propylene
- Propylene carbonate,99.5%
- PROPYLENE CARBONATE pure
- Diester of 2-carboxymethoxy thioxanthone and Poly tetra- methyleneglycol 250
- Propylene carbonate,1,2-Propanediol cyclic carbonate, 4-Methyl-1,3-dioxolan-2-one
- Propylene carbonate, 99%, SpcDry, Water≤50 ppM (by K.F.), SpcSeal
- Propylene carbonate, 99.5%, SpcDry, with Molecular sieves, Water≤50 ppM (by K.F.), SpcSeal
- 1.2-Propylene
- Propylene carbonate for HPLC, 99.7%
- Propylene carbonate ReagentPlus(R), 99%
- Propylene carbonate Vetec(TM) reagent grade, 98%
- Propylene carbonate >=99%, acid <10 ppm, H2O <10 ppm
- (±)-Methyl-1,3-dioxolan-2-one
- (R,S)-4-Methyl-[1,3]dioxolan-2-one