成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

2,2'-Methylen-bis(3,4,6-trichlorphenol)

Hexachlorophene Struktur
70-30-4
CAS-Nr.
70-30-4
Bezeichnung:
2,2'-Methylen-bis(3,4,6-trichlorphenol)
Englisch Name:
Hexachlorophene
Synonyma:
b32;at7;AT-7;B 32;G-11;G-II;Nabac;AT-17;Fomac;Hexide
CBNumber:
CB8687902
Summenformel:
C13H6Cl6O2
Molgewicht:
406.9
MOL-Datei:
70-30-4.mol

2,2'-Methylen-bis(3,4,6-trichlorphenol) Eigenschaften

Schmelzpunkt:
163-165 °C(lit.)
Siedepunkt:
519.9°C (rough estimate)
Dichte
1.6065 (rough estimate)
Brechungsindex
1.5550 (estimate)
Flammpunkt:
11 °C
storage temp. 
2-8°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
Aggregatzustand
crystalline
pka
pKa 4.89 ± 0.02(H2O,t = 25.0±0.1,I=0.1(NaCl)) (Uncertain)
Farbe
off-white to tan
Wasserl?slichkeit
19mg/L(25 ºC)
maximale Wellenl?nge (λmax)
300nm(MeOH)(lit.)
Merck 
14,4680
BRN 
2064407
Stabilit?t:
Stable. Incompatible with alkalies, akaline earths, tweens, strong oxidizers.
CAS Datenbank
70-30-4(CAS DataBase Reference)
IARC
3 (Vol. 20, Sup 7) 1987
NIST chemische Informationen
EPA chemische Informationen
Hexachlorophene (70-30-4)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T,N,F
R-S?tze: 24/25-50/53-52/53-39/23/24/25-23/24/25-11-51/53
S-S?tze: 20-37-45-60-61-36/37-16
RIDADR  UN 2875 6.1/PG 3
WGK Germany  3
RTECS-Nr. SM0700000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29072990
Giftige Stoffe Daten 70-30-4(Hazardous Substances Data)
Toxizit?t LD50 in adult male, female rats (mg/kg): 66, 57 orally (Gaines, Linder)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H410 Sehr giftig für Wasserorganismen mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 1 Warnung GHS hazard pictogramssrc="/GHS09.jpg" width="20" height="20" /> P273, P391, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P273 Freisetzung in die Umwelt vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

2,2'-Methylen-bis(3,4,6-trichlorphenol) Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

GERUCHLOSES, WEISSES KRISTALLINES PULVER

CHEMISCHE GEFAHREN

Zersetzung beim Erhitzen oder Verbrennen unter Bildung giftiger und reizender Rauche mit Chlorwasserstoff.

ARBEITSPLATZGRENZWERTE

TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).

AUFNAHMEWEGE

Aufnahme in den K?rper durch Inhalation, über die Haut und durch Verschlucken.

INHALATIONSGEFAHREN

Verdampfung bei 20°C vernachl?ssigbar; eine gesundheitssch?dliche Partikelkonzentration in der Luft kann jedoch beim Versprühen oder Dispergieren schnell erreicht werden, besonders als Pulver.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
M?glich sind Auswirkungen auf das Zentralnervensystem mit nachfolgenden Kr?mpfen und Atemversagen.

WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION

Wiederholter oder andauernder Hautkontakt kann zu Dermatitis und Hautsensibilisierung führen. Wiederholte oder andauernde Inhalation kann asthmatische Beschwerden hervorrufen. M?glich sind Auswirkungen auf das Nervensystem mit nachfolgenden Gewebesch?den und Erblindung. Tierversuche zeigen, dass die Substanz m?glicherweise Fehlbildungen bei Neugeborenen hervorrufen kann.

LECKAGE

Verschüttetes Material in abdichtbaren Beh?ltern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgf?ltig sammeln. An sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Pers?nliche Schutzausrüstung: Atemschutzger?t, P3-Filter für giftige Partikel.

R-S?tze Betriebsanweisung:

R24/25:Giftig bei Berührung mit der Haut und beim Verschlucken.
R50/53:Sehr giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
R52/53:Sch?dlich für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.

S-S?tze Betriebsanweisung:

S20:Bei der Arbeit nicht essen und trinken.
S37:Geeignete Schutzhandschuhe tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Beschreibung

Hexachlorophene (HCP) is a chlorinated bisphenol antiseptic and was introduced for use as an antibacterial component in drug and cosmetic products in 1941. It has bacteriostatic activity against gram-positive organisms (e.g., staphylococcus) but not against gram-negative organisms. HCP is readily absorbed orally and through the skin of humans, especially skin of premature infants or damaged skin. Hexachlorophene is a neurotoxicant, and symptomology may include lethargy, muscle weakness, irritability, cerebral edema, and paralysis leading to coma and death. The US Food and Drug Administration restricted the use of hexachlorophene preparation to ≤0.1% in 1972 and approved it for surgical scrubbing and handwashing. HCP is no longer used extensively in hospitals, rest homes, etc., because of its toxicity.

Chemische Eigenschaften

Hexachlorophene is a crystalline solid com pound.

Verwenden

Hexachlorophene is a topical antiseptic in germicidal soaps, creams, deodorants, cleansers, shampoos, after-shave creams, pHisoHex surgical cleanser and in veterinary medicine.

Indications

Hexachlorophene is a bacteriostatic antiseptic effective against gram-positive organisms, specifically Staphylococcus. It has a cumulative and sustained effect. Although it has a slow onset of action, with repeated use a film develops on the skin that has long-acting properties. It is not effective against gram-negative organisms or yeast. It is postulated to affect bacterial electron transport and membrane function. With repeated use, it penetrates through the stratum corneum.
It is often used for preoperative surgical scrubbing. One retrospective study showed that it may be teratogenic if used excessively by pregnant women, although there have been no subsequent, well-controlled studies that substantiate this. It should not be used in infants, particularly those who are premature or have dermatoses. It is toxic to tissues when applied to open wounds.

synthetische

Hexachlorophene is formed by reaction of 2,4,5-trichlorophenol with paraformaldehyde in fuming sulfuric acid (20% SO3) at 65–135 ℃. Hexachlorophene is a strong bacteriostat which also has a microbicidal effect at high concentrations. The use of Hexachlorophene as an antimicrobial agent in cosmetics, medicinal soaps, detergent solutions, and textiles has, however, been discontinued because of its toxicity.

Definition

ChEBI: An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Weltgesundheitsorganisation (WHO)

Hexachlorophene, an antimicrobial agent, was introduced in 1948 in proprietary liquid preparations and powders and was subsequently used extensively as a topical antiseptic. By the early 1970s its use in infants had been conclusively demonstrated to cause encephalopathy as a result of transdermal absorption. More recently it has been suggested that the drug has a teratogenic potential. Many regulatory authorities have placed rigorous restrictions on the medicinal use of hexachlorophene, particularly in preparations intended for infants. However, its use still commonly remains permissible at low concentrations as a preservative in toiletries and cosmetics. (Reference: (WHODI) WHO Drug Information, 3, 6, 1978)

Allgemeine Beschreibung

A white free-flowing odorless powder. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.

Air & Water Reaktionen

Insoluble in water.

Reaktivit?t anzeigen

Hexachlorophene is incompatible with strong oxidizers. Hexachlorophene forms salts with alkalis and alkaline earths.

Hazard

FDA prohibits use unless prescribed by a physician. Questionable carcinogen.

Health Hazard

Inhalation of dust is poisonous; irritating to mucous membranes. Eye and skin irritant. Poisonous if swallowed. Symptoms following ingestion include anorexia, nausea, vomiting, abdominal cramps, and diarrhea. Dehydration may be severe and may be associated with shock.

m?gliche Exposition

HCP has been used as an antibacterial agent in a wide variety of consumer products, including soaps and deodorants; as a disinfectant. It has also been used as an antifungal agent to treat various citrus fruits and vegetables.

Environmental Fate

HCP adsorbs very strongly to soil and is not expected to leach to groundwater. It may undergo slow photodegradation on the surface of soils and water based on its absorption of light (290 nm). No information is available on its biodegradation in soil or surface water. HCP released in water adsorbs very strongly to sediments and may bioconcentrate in aquatic organisms. It has an estimated bioconcentration factor of 317 000. HCP is not expected to hydrolyze or to significantly evaporate from water. When released into the air, HCP is expected to be mainly in the particle-sorbed state due to its low vapor pressure and high estimated Koc. It is expected to be removed from the atmosphere primarily by dry deposition, but it is also degraded by reaction with photochemically produced hydroxyl radicals, with an estimated vapor phase half-life of 2.5 days.

Versand/Shipping

UN2875 Hexachlorophene, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

l?uterung methode

It forms needles from MeOH, C2H4Cl2, or toluene. The diacetate has m 175-176o (EtOH). A disinfectant is also available in MeOH (5mg/L). [Beilstein 6 III 5407, 6 IV 6659.]

Inkompatibilit?ten

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste disposal

Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste con taining this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treat ment, and waste disposal.

2,2'-Methylen-bis(3,4,6-trichlorphenol) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2,2'-Methylen-bis(3,4,6-trichlorphenol) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 120)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9636 58
Pharmahands (Taizhou) Co., Ltd.
+86 523-86200360
CHINA 358 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168
chem1022@hengdian-group.com China 1478 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58

70-30-4(2,2'-Methylen-bis(3,4,6-trichlorphenol))Verwandte Suche:


  • Hexachlorophene (500 mg)
  • 6,6'-Methylenebis(2,4,5-trichlorophenol)
  • NSC 49115
  • NSC 9887
  • 3,3',5,5',6,6'-Hexachloro-2,2'-dihydroxydiphenylmethane 2,2'-Methylenebis(3,4,6-trichlorophenol)
  • 4-Amino-1,5-dimethylpyrazole 2HCl
  • 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane
  • 2,2’,3,3’,5,5’-Hexachloro-6,6’-dihydrosydiphenylmethane
  • b&bfleakontrollerfordogsonly
  • b32
  • Bilevon
  • Bis(2-Hydroxy-3,5,6-trichlorophenyl)methane
  • Bis(3,5,6-trichloro-2-hydroxyphenyl)methane
  • Bis[3,4,6-trichlorophenol], 2,2'-methylene-
  • Bis-2,3,5-trichlor-6-hydroxyfenylmethan
  • bis-2,3,5-trichloro-6-hydroxyfenylmethan(czech)
  • Bivelon
  • blockadeantibacterialfinish
  • brevityblueliquidbacteriostaticscouringcream
  • brevityblueliquidsanitizingscouringcream
  • SERIBAK
  • NABAC(R)
  • Hexabalm
  • Hexachlorofen
  • hexachlorofen(czech)
  • Hexachlorophane
  • HexachlorophaneDerl
  • Hexachlorphene
  • Hexafen
  • hexaphene-lv
  • Hexide
  • Hexophene
  • Hexosan
  • hilocatfleapowder
  • hilofleapowder
  • Isobac 20
  • Methane, bis(2,3,5-trichloro-6-hydroxyphenyl)
  • methane,bis(2,3,5-trichloro-6-hydroxyphenyl)
  • Methylenebis(3,4,6-trichlorophenol)
  • Nabac
  • Nabac 25 ec
  • nabac25ec
  • NCI-C02653
  • Neosept V
  • neoseptv
  • pedigreedogshampoobar
  • Phenol, 2,2'-methylenebis(3,5,6-trichloro-
  • Phenol, 2,2'-methylenebis*3,4,6-trichloro-
  • Phenol, 2,2'-methylenebis[3,4,6-trichloro-
  • Phisodan
  • Phisohex
  • Rcra waste number U132
  • rcrawastenumberu132
  • Ritosept
  • Septisol
  • Septofen
  • Soy-dome
  • stapheneo
Copyright 2019 ? ChemicalBook. All rights reserved