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ALOSETRON

ALOSETRON Struktur
122852-42-0
CAS-Nr.
122852-42-0
Englisch Name:
ALOSETRON
Synonyma:
ALOSETRON;GR-68755X;GR-68755;ALOSETRON USP/EP/BP;Alosetron (GR-68755X;GR 68755; GR 68755X; LOTRONEX;GR-68755;GR68755;9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)- 1,2,3,9-Tetrahydro-;5-METHYL-2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]-3,4-DIHYDROPYRIDO[4,3-B]INDOL-1-ONE;9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)-1,2,3,9-Tetrahydro-Carbazol-4-One Hydrochloride;5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one;1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-
CBNumber:
CB8149787
Summenformel:
C17H18N4O
Molgewicht:
294.35
MOL-Datei:
122852-42-0.mol

ALOSETRON Eigenschaften

Schmelzpunkt:
238-240 °C
Siedepunkt:
648.1±55.0 °C(Predicted)
Dichte
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO
Aggregatzustand
Powder
pka
14.10±0.10(Predicted)

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36

ALOSETRON Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

crystalline powder

Verwenden

Anti-emetic.

Definition

ChEBI: A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.

Indications

Alosetron (Lotronex) is a 5-HT3 receptor antagonist. Blocking this receptor results in decreased GI motility. Alosetron received FDA approval in February 2000 for the treatment of women with diarrhea-predominant IBS. In November 2000, at the request of the FDA, the drug was voluntarily withdrawn due to reported cases of ischemic colitis, including some fatalities.

ALOSETRON Upstream-Materialien And Downstream Produkte

Upstream-Materialien

1-TRITYL-1H-IMIDAZOLE-4-METHANOL Natriumhydrid Polyphosphorsuren Thionyldichlorid Maleins?ure Hydroxylammoniumchlorid 2-Methoxy-ethanol

Downstream Produkte

ALOSETRON Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 83)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29815 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32024 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Xi'an MC Biotech, Co., Ltd. 		029-89275612 +8618991951683
 mcbio_sales@163.com China 2251 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167
 1026@dideu.com China 7724 58
Baoji Guokang Bio-Technology Co., Ltd. 		0917-3909592 13892490616
 gksales1@gk-bio.com China 9315 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118
 xie@china-sinoway.com China 988 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763
 sales@tnjchem.com China 25356 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58

122852-42-0()Verwandte Suche:

  • ALOSETRON
  • ALOSETRON 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
  • 5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
  • 5-METHYL-2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]-3,4-DIHYDROPYRIDO[4,3-B]INDOL-1-ONE
  • GR-68755X;GR-68755
  • Alosetron (GR-68755X
  • GR 68755; GR 68755X; LOTRONEX;GR-68755;GR68755
  • 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-
  • ALOSETRON USP/EP/BP
  • 9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)- 1,2,3,9-Tetrahydro-
  • 9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)-1,2,3,9-Tetrahydro-Carbazol-4-One Hydrochloride
  • 122852-42-0
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