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Lyase, Chondroitin ABC

CHONDROITINASE ABC Struktur
9024-13-9
CAS-Nr.
9024-13-9
Bezeichnung:
Lyase, Chondroitin ABC
Englisch Name:
CHONDROITINASE ABC
Synonyma:
EC 4.2.2.4;units/mg solid;CHONDROITINASE ABC;chondroitinase ABC I;CHONDROITIN ABC LYASE;Lyase, chondroitin ABC;chondroitinase-abc bsa free;Chondroitinase ABC, Recomb.;lyophilized powder, 0.3-3 chondroitin-sulfate-ABC endolyase
CBNumber:
CB7143258
Summenformel:
NULL
Molgewicht:
0
MOL-Datei:
Mol file

Lyase, Chondroitin ABC Eigenschaften

storage temp. 
-20°C
L?slichkeit
0.01% bovine serum albumin aqueous (BSA) solution: soluble
Aggregatzustand
lyophilized powder
Farbe
White to off-white

Sicherheit

S-S?tze: 22-24/25
WGK Germany  3
10-21

Lyase, Chondroitin ABC Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Chondroitinase ABC from Sigma has been used to digest O-linked chondroitin sulfate-like glycosaminoglycan (CSGAG). The enzyme has also been used to digest glycosaminoglycan chains in proteoglycans during the construction and expression of a recombinant versican gene in mammalian systems. Furthermore, it has been used to digest chondroitin sulfate in the proteoglycan complexes. The enzyme has also been used in the removal of glycan chains from aggrecan, which eliminates the axon growth-inhibitory effect of aggrecan.

Biochem/physiol Actions

Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl (or (1-3)-α-L-iduronosyl) linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate. However, it acts slowly on hyaluronate. The molecular weight is approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid. The optimal temperature is 37 °C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activator of the enzyme.

Lyase, Chondroitin ABC Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lyase, Chondroitin ABC Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 26)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
sj_scrc@sinopharm.com China 9815 79
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939
shenlinxing@macklin.cn China 16166 55
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Beijing OKA biological technology co., LTD 010-010-010-62971590 18548936886
jack@oka-vip.com China 6897 58
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4696 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376
1046@dideu.com China 10007 58
JiangSu Star Science Co.,Ltd 400-400-605-7200-7200 17312445705
sales022@b2star.com China 3761 58

9024-13-9(Lyase, Chondroitin ABC)Verwandte Suche:


  • CHONDROITINASE ABC
  • CHONDROITIN ABC LYASE
  • EC 4.2.2.4
  • chondroitinase abc F. proteus vulgaris
  • Chondroitinase ABC from Proteus vulgaris
  • Chondroitinase ABC, Proteus vulgaris*Not available Japan*
  • Chondroitinase ABC, Recomb.
  • chondroitinase-abc bsa free
  • Lyase, chondroitin ABC
  • CHONDROITIN ABC LYASE, FROM PROTEUS VULGARIS
  • Chondroitinase ABC from Proteus vulgaris,Chondroitin ABC Lyase
  • chondroitin-sulfate-ABC endolyase
  • Chondroitinase ABC from Proteus vulgaris, Recombinant
  • Native Proteus vulgaris Chondroitinase ABC
  • chondroitinase ABC I
  • lyophilized powder, 0.3-3 
  • units/mg solid
  • 9024-13-9
  • Biochemicals and Reagents
  • BioChemical
  • Application Index
  • Carbohydrate hydrolysis & PTM analysis
  • Carbohydrate and PTM Analysis
  • Carbohydrate Hydrolysis
  • Enzymes, Inhibitors, and Substrates
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