10-Gingerol
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- CAS-Nr.
- 23513-15-7
- Englisch Name:
- 10-Gingerol
- Synonyma:
- 10-GINGEROL;GINGEROL, 10-;10-Gingerol ,98%;10-GINGEROL, HPLC 98%;(+)-(S)-[10]-Gingerol;10-Gingerol USP/EP/BP;[10]-Gingerol Standard;10]-Gingerol >=95% (HPLC);Propionic Acid Impurity 1;10-Gingerol, 98%, from Zingiber officinale Roscoe
- CBNumber:
- CB6399377
- Summenformel:
- C21H34O4
- Molgewicht:
- 350.49
- MOL-Datei:
- 23513-15-7.mol
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10-Gingerol Eigenschaften
- Schmelzpunkt:
- 56-58 °C
- Siedepunkt:
- 499.7±35.0 °C(Predicted)
- Dichte
- 1.037±0.06 g/cm3(Predicted)
- Flammpunkt:
- 166℃
- storage temp.
- 2-8°C
- L?slichkeit
- methanol: soluble5mg/mL, clear, colorless
- Aggregatzustand
- Solid
- pka
- 10.02±0.20(Predicted)
- Farbe
- Yellow
- Wasserl?slichkeit
- practically insoluble in water
- InChIKey
- AIULWNKTYPZYAN-SFHVURJKSA-N
- LogP
- 4.900 (est)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| R-S?tze: |
53 |
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| S-S?tze: |
24/25 |
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| WGK Germany |
3 |
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| HS Code |
29145019 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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10-Gingerol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
10-Gingerol is a phenol that has been found in
Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC
50s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against
M. avium and
M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells.
Verwenden
(+)-(S)-[10]-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation.
Biochem/physiol Actions
[10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.
10-Gingerol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
10-Gingerol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 224)Lieferanten
23513-15-7()Verwandte Suche:
- 10-GINGEROL, HPLC 98%
- 10-GINGEROL
- 5-HYDROXY-1-(4-HYDROXY-3-METHOXYPHENYL)-3-TETRADECANONE
- (5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one
- (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
- (S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one
- (S)-12-Oxo-14-(3-methoxy-4-hydroxyphenyl)tetradecane-10-ol
- (5S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)tetradecan-3-one
- (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
- 10-Gingerol ,98%
- 5-hydroxy-1-(4-hydroxy-3-Methoxyphenyl)tetradecan-3-one
- (S)-5-hydroxy-1-(4-hydroxy-3-Methoxyphenyl)tetradecan-3-one
- (+)-(S)-[10]-Gingerol
- (s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
- GINGEROL, 10-
- 10-Gingerol, 98%, from Zingiber officinale Roscoe
- [10]-Gingerol Standard
- 3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
- 10]-Gingerol >=95% (HPLC)
- 10-Gingerol USP/EP/BP
- Propionic Acid Impurity 1
- 23513-15-7
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- The group of Ginerols
- Miscellaneous Natural Products
