Spiperon
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- CAS-Nr.
- 749-02-0
- Bezeichnung:
- Spiperon
- Englisch Name:
- SPIPERONE
- Synonyma:
- r5147;Spiperon;SPIPERONE;Spiropitan;Luopenglong;SPIROPERIDOL;Spiperone-d5;SpiperoneHCl;Spiroperidone;Spiperone, 10 mM in DMSO
- CBNumber:
- CB5748844
- Summenformel:
- C23H26FN3O2
- Molgewicht:
- 395.47
- MOL-Datei:
- 749-02-0.mol
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Spiperon Eigenschaften
- Schmelzpunkt:
- 190-193.60C
- Siedepunkt:
- 630.6±55.0 °C(Predicted)
- Dichte
- 1.1714 (estimate)
- storage temp.
- Store at RT
- L?slichkeit
- H2O: slightly soluble0.2mg/mL
- pka
- pKa 8.31 (Uncertain);9.09 (Uncertain)
- Aggregatzustand
- solid
- Farbe
- light yellow
- Wasserl?slichkeit
- 32mg/L(22 ºC)
Spiperon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
Off-White Solid
Verwenden
Spiperone is an antipsychotic.
Definition
ChEBI: An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Allgemeine Beschreibung
Spiperone is a butyrophenone antipsychotic agent. It induces calcium-dependent chloride secretion in the airway and functions as a potential therapeutic target for cystic fibrosis.
Biologische Aktivit?t
5-HT 2A serotonin and selective D 2 -like dopamine receptor antagonist (K i values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively). Antipsychotic.
Spiperon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Spiperon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 64)Lieferanten
749-02-0(Spiperon)Verwandte Suche:
- 1,3,8-triazaspiro(4.5)decan-4-one,8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl
- 4’-fluoro-4-(4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl)-butyrophenon
- Spiperone-d5
- 8-(3-p-fluorobenzoyl-1-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decane
- 8-triazaspiro(4.5)decan-4-one,8-(3-(p-fluorobenzoyl)propyl)-1-phenyl-3
- r5147
- 8-[3-(P-FLUOROBENZOYL)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE
- 4-PHENYL-8-[3-(4-FLUOROBENZOYL)-PROPYL]-1-OXO-2,4,8-TRIAZASPIRO[4,5]DECANE
- SPIPERONE
- SPIROPERIDOL
- R 5147, Spiroperidol, 8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
- SpiperoneHCl
- 8-[4-(4-Fluprophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
- Spiroperidone
- Spiropitan
- 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
- 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
- Spiperon
- ethyl4-(4-methoxy-3-methylphenyl)-2,8-dioxobutanoate
- Serotonin Receptor,pharmacological,Spiperone,inhibit,neurology diseases,5-HT Receptor,5-HT1A,5-HT2A,5-hydroxytryptamine Receptor,dopamine D2,Inhibitor,Dopamine Receptor
- Luopenglong
- Spiperone, 10 mM in DMSO
- 749-02-0
- C23H26FN3O2HCl
- C23H26FN3O2
- Serotonin receptor
- Amine
- Aromatics
- Heterocycles
- ILOSONE
- Intermediates & Fine Chemicals
- Pharmaceuticals
