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corticorelin ovine

corticorelin ovine Struktur
121249-14-7
CAS-Nr.
121249-14-7
Englisch Name:
corticorelin ovine
Synonyma:
corticorelin ovine;Corticorelin ovine triflutate;CRF (ovine) Corticorelin (ovine)
CBNumber:
CB52130412
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

corticorelin ovine Eigenschaften

Sicherheit

corticorelin ovine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Diagnostic aid(adrenocortical insufficiency); diagnostic aid (Cushing’s syndrome); hormone (corticotropin-releasing).

Biologische Funktion

The primary function of corticotropin-releasing factor (CRF), a hypothalamic 41-peptide, is the regulation of the release of adrenocorticotropin hormone (ACTH) from the anterior pituitary gland, which then stimulates the release of hydrocortisone from the adrenal gland. The human peptide (hCRF) and the similar sequence found in sheep (oCRF) have been prepared by synthesis. The ovine form of the hormone, however, has replaced the human form because of its longer half-life and greater potency; hCRF is no longer commercially available.
Usually, ACTH deficiency in humans is associated with a pituitary disorder rather than with a deficiency of CRF, and oCRF can be used to distinguish between pituitary hypersecretion of ACTH (Cushing's disease) and ectopic ACTH secretion, both of which are conditions that cause a hypersecretion of hydrocortisone. In the case of ectopic ACTH secretion, the administration of oCRF will elicit little to no response in the production of ACTH and hydrocortisone. Therefore, synthetic oCRF trifluoroacetate salt is marketed as a diagnostic agent for patients with ACTH dependent Cushing's syndrome.

corticorelin ovine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


corticorelin ovine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 999 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696
info@hanhongsci.com China 42958 64
Cellmano Biotech Limited 0551-65326643 18156095617
info@cellmano.com China 1011 55
Nanjing Peptide Biotech Ltd. 025-025-58361106-805-805 13082558573
liugang@njpeptide.com China 9980 55
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com
meitaochem@126.com China 19103 58
Gill polypeptide biopharmaceutical (dalian) co., LTD 021-61263455 13167021076
amy@glschina.com China 8745 58
Nanjing Shizhou Biology Technology Co.,Ltd 13675144456
alan.chow@synzest.com China 9470 58
Nanjing Yuanpeptide Biotech Co.,Ltd. 18168071971
support@yuan-peptide.com China 2980 58
Chengdu Jinglin Biotechnology Co., Ltd. 17711399154
3211919385@qq.com China 1815 58
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