Cyproheptadinhydrochlorid
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Cyproheptadinhydrochlorid Eigenschaften
- Schmelzpunkt:
- 254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- ethanol: soluble
- Aggregatzustand
- solid
- Farbe
- Crystals from EtOH/Et2O
- Wasserl?slichkeit
- Soluble in water (15mM)
- Stabilit?t:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xn | ||
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R-S?tze: | 22-36/37/38 | ||
S-S?tze: | 26-36 | ||
RIDADR | UN 2811 6.1/PG 3 | ||
WGK Germany | 3 | ||
RTECS-Nr. | TM7050000 | ||
HazardClass | 6.1(b) | ||
PackingGroup | III | ||
Toxizit?t | LD50 orl-rat: 295 mg/kg DRUGAY 6,340,82 |
Bildanzeige (GHS) |
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Cyproheptadinhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Cyproheptadine hydrochloride is an antihistamine in which antiserotonin activity has been demonstrated both in vivo and in vitro. As yet, however, there is no evidence that this action contributes to clinical therapeutic effects. Anticholinergic and sedative effects are observed. Cyproheptadine may be more effective than other H1 blockers in the management of cold urticaria.Definition
ChEBI: The hydrochloride salt of cyproheptadine. Note that the drug named cyproheptadine hydrochloride generally refers to cyproheptadine hydrochloride sesquihydrate.Allgemeine Beschreibung
Cyproheptadinehydrochloride, 4-(5H-dibenzo-[a,d]-cyclohepten-5-ylidine)-1-methylpiperidine hydrochloride sesquihydrate(Periactin), is slightly soluble in water and sparingly solublein alcohol.Cyproheptadine possesses both antihistamine and antiserotoninactivity and is used as an antipruritic agent. It isindicated for the treatment of hypersensitivity reactions,perennial, and seasonal allergic rhinitis; vasomotor rhinitis;allergic conjunctivitis, uncomplicated allergic skin manifestationsof urticaria and angioedema; amelioration of allergicreactions to blood or plasma; and cold urticaria. It is alsoused off-label for nightmares associated with posttraumaticstress disorder (PTSD), prevention of migraine, suppressionof vascular headaches, and appetite stimulation. Sedation isthe most prominent side effect, and this is usually brief, disappearingafter 3 or 4 days of treatment.
Biologische Aktivit?t
Non-selective 5HT 2 antagonist, migraine prophylactic.Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: jaundice, liver function tests impaired, gastrointestinal effects. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. WhenheatedCyproheptadinhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Essigs?ureanhydrid
Hydrogenchlorid
Magnesium
Natriumhydroxid
4-Chloropiperidine hydrochloride
Bromethan
5-(1-Methyl-4-Piperidyl)5H-Dibenzo
Downstream Produkte
Cyproheptadinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 229)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8804 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12829 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531153977 |
allison@yan-xi.com | China | 5855 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5888 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 997 | 58 |
Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 |
kyra@quanjinci.com | China | 1512 | 58 |
Yujiang Chemical (Shandong) Co.,Ltd. | +86-17736087130 +86-18633844644 |
catherine@yjchem.com.cn | China | 992 | 58 |
Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 |
niki@zlchemi.com | China | 3712 | 58 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29871 | 58 |
969-33-5(Cyproheptadinhydrochlorid)Verwandte Suche:
4,9-Dihydro-4-(1-methylpiperidin-4-yliden)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-onfumarat
4-(4-Chlorphenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenylpiperidin-1-butyramidmonohydrochlorid
Methyl[3-phenyl-3-[4-(trifluormethyl)phenoxy]propyl]ammoniumchlorid
[2-Hydroxy-3-(naphthyloxy)propyl]isopropylammoniumchlorid
4-(5H-Dibenzo(a,d)cyclohepten-5-yliden)-1-methyl-piperidin
- CYPROHEPTADINE HYDROCHLORIDE(GRP B SL NO.1124)
- 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride
- 4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride
- 4-(5h-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-piperidinhydrochloride
- cyproheptadienehydrochloride
- nuran
- CyproheptadineHclCyproheptadineHclBp
- CYPROHEPTADINEHYDROCHLORIDE(ANHYDROUS)
- ANAREXOL
- CYPROHEPTADINE HCL BP
- Cyproheptadine hydrochloride (Periactin)
- Cyproheptadine hydrochloride
- periactinhydrochloride
- periactinolhydrochloride
- periactinsyrup
- peritol
- Cycloheptadine Hydrochloride
- Cyproheptadine hydrochloride,CYPROHEPTADINE HCL, periactinolhydrochloride
- 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride
- Cyproheptadine hydrochloride USP/EP/BP
- Cyproheptadine hydrochloride USP/EP/BP USP/EP/BP
- 1-Methyl-4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine hydrochloride
- CYPROHEPTADINE HCL
- 4-(5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDINE)-METHYLPIPERIDINE HYDROCHLORIDE
- Cyproheptadinhydrochlorid
- Cyheptadine hydrochloride
- Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (1:1)
- Cycloheptadine HCl
- Cyproheptadine hydrochloride, 10 mM in DMSO
- 969-33-5
- 354-29-4
- C21H21NHCl1H2O
- C21H21NClH
- Building Blocks
- Heterocyclic Building Blocks
- Piperidines
- Serotonin receptor
- Active Pharmaceutical Ingredients