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N-4-Aminobenzoyl-L-glutaminsure

N-(p-Aminobenzoyl)glutamic acid Struktur
4271-30-1
CAS-Nr.
4271-30-1
Bezeichnung:
N-4-Aminobenzoyl-L-glutaminsure
Englisch Name:
N-(p-Aminobenzoyl)glutamic acid
Synonyma:
N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID;Methotrexate EP Impurity K;(2S)-2-(4-Aminobenzamido)pentanedioic Acid;(2S)-2-[(4-Aminobenzoyl)amino]pentanedioic Acid;NSC 71042;H-4-ABZ-GLU-OH;Folic acid iMpurity A;Methotrexate Impurity K;Folic Acid EP Impurity A;P-aminobenzoyl glutamate
CBNumber:
CB2193546
Summenformel:
C12H14N2O5
Molgewicht:
266.25
MOL-Datei:
4271-30-1.mol

N-4-Aminobenzoyl-L-glutaminsure Eigenschaften

Schmelzpunkt:
~175 °C (dec.)
alpha 
-15 º (c=2% in 0.1N HCl)
Siedepunkt:
409.45°C (rough estimate)
Dichte
1.2846 (rough estimate)
Brechungsindex
1.6660 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
Aqueous Base (Sparingly), Aqueous Acid (Sparingly), DMSO (Sparingly)
Aggregatzustand
Solid
pka
3.50±0.10(Predicted)
Farbe
White to Light
Merck 
14,426
BRN 
2816320
Stabilit?t:
Hygroscopic
InChIKey
GADGMZDHLQLZRI-VIFPVBQESA-N
CAS Datenbank
4271-30-1(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
R-S?tze: 36/37/38
S-S?tze: 26-36/37/39
WGK Germany  3
HS Code  2924296000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

N-4-Aminobenzoyl-L-glutaminsure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

Light Tan Waxy Solid

Verwenden

Major metabolite of 5-Methyltetrahydrofolic Acid

Definition

ChEBI: A dipeptide resulting from the formal condensation of the carboxylic acid group of 4-aminobenzoic acid with the amino group of L-glutamic acid.

l?uterung methode

Crystallise the acid from H2O. Also purify it by dissolving 2.7g in H2O (130mL), adding aqueous NaOH to pH 5.5 and adding portionwise a solution of 0.5M CuSO4 to complete precipitation of the Cu salt. This salt is filtered off, suspended in H2O and H2S is bubbled through to precipitate CuS, filter, evaporate and recrystallise the residue from H2O. It has max (H2O) at 273nm. [Backer & Houtman Recl Trav Chim Pays-Bas 70 738, 743 1951, Beilstein 14 IV 1153.]

N-4-Aminobenzoyl-L-glutaminsure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-4-Aminobenzoyl-L-glutaminsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 453)Lieferanten
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TAIZHOU DKD CHEMICAL CO., LTD.
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4271-30-1(N-4-Aminobenzoyl-L-glutaminsure)Verwandte Suche:


  • N-(p-Aminobenzoyl)glutamic acid
  • 2-[(4-aminobenzoyl)amino]glutaric acid
  • 2-[(4-azanylphenyl)carbonylamino]pentanedioic acid
  • 4-AMINOBENZOYLGLUTAMIC ACID
  • 4-AMINOBENZOIC GLUTAMIC ACID
  • 4-aminobenzoyl-L-glutamic acid
  • NSC 71042
  • (S)-2-(4-AMinobenzaMido)pentanedioic acid
  • Folic acid iMpurity A
  • Folic acid iMpurity A N-(4-AMinobenzoyl)-L-glutaMic acid
  • N-(P-Aminobenzoyl)-L-glutamic acidN-(P-Aminobenzoyl)-L-(+)glutamicacid EuE
  • N-(4-aminobenzoyl)-L-Glutamic acid (Folic Acid Imp A)
  • 4-Aminobenzoylglutamic Acid (50 mg)
  • Methotrexate Impurity K
  • H-4-ABZ-GLU-OH
  • N-(P-AMINOBENZOYL)-L-GLUTAMIC ACID
  • P-AMINOBENZOYL-L-GLUTAMIC ACID
  • P-AMINO BENZAMIDE GLUTAMIC ACID
  • N-(4-Aminobenzoyl)-L-Glutaminic Acid
  • L-Glutamic acid, N-(4-aminobenzoyl)-
  • Methotrexate Impurity 11(EP-K)
  • (2S)-2-[(4-aminophenyl)formamido]pentanedioic acid
  • Methotrexate Impurity K (Folinic Acid Impurity A)
  • Calcium Levofolinate EP Impurity A
  • Calcium Levofolinate Impurity 1(Calcium Levofolinate EP Impurity A)
  • N-(4-carbamoyl)-L-glutamic acid
  • Folinic Acid Impurity A (Methotrexate Impurity K)
  • N-(4-Aminobenzoyl)-L-glutamic Acid >
  • (2S)-2-[(4-Aminobenzoyl)amino]penta
  • Folic acid impurity A CRS
  • N-4-Aminobenzoyl-L-glutaminsure
  • Folinic Acid Impurity A (4-Aminobenzoyl Glutamic Acid)
  • Impurity A of Calcium Levofolinate
  • Levofolinate EP Impurity A
  • Folic Acid EP Impurity A
  • Folic Acid Impurity 1(Folic Acid EP Impurity A)
  • N-(4-aminobenzoyl)-L-glutamicaci
  • N-p-aminobenzoyl-L-glutamic acid USP/EP/BP
  • N-(p-Aminobenzoyl)glutamic acid USP/EP/BP
  • Methotrexate Impurity 11(Methotrexate EP Impurity K)
  • Para amino-benzoyl glutamate
  • Methotrexate EP Impurity K (Folic Acid EP Impurity A)
  • Folic Acid EP Impurity A (Methotrexate EP Impurity K)
  • N-(4-Aminobenzoyl)-L-glutamic acid, ≥98% (TLC)
  • 4-Aminobenzoylglutamic Acid (F0M031)
  • Folic acid Impurity AQ: What is Folic acid Impurity A Q: What is the CAS Number of Folic acid Impurity A Q: What is the storage condition of Folic acid Impurity A
  • 4-Aminobenzoylglutamic Acid (1019870)
  • (2S)-2-[(4-Aminobenzoyl)amino]pentanedioic Acid
  • (2S)-2-(4-Aminobenzamido)pentanedioic Acid
  • Methotrexate EP Impurity K
  • N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID
  • Methotrexate EP Impurity K (Folinic Acid EP Impurity A)
  • N-(4-aminobenzoyl) -L-glutamate
  • N-(p-Aminobenzoyl)glutamicaci
  • Calcium Folinate EP Impurity A
  • Folinic Acid Impurity A (Methotrexate EP Impurity K)
  • Folic Acid Hydrate EP Impurity A
  • Methotrexate EP Impurity K(Folic Acid EP Impurity A、Levofolinate EP Impurity A)
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