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N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure

L-Tetrahydrofolic Acid Struktur
135-16-0
CAS-Nr.
135-16-0
Bezeichnung:
N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure
Englisch Name:
L-Tetrahydrofolic Acid
Synonyma:
TETRAHYDROFOLIC ACID;(6S)-Tetrahydrofolic acid;C00101;(6S)-Thfa;L-5,6,7,8;l-amino)benzoyl);70% when packaged);Tetrahydofolic acid;Tetrahydrofolic acide;L-Tetrahydrofolic Acid
CBNumber:
CB6259109
Summenformel:
C19H23N7O6
Molgewicht:
445.43
MOL-Datei:
135-16-0.mol

N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure Eigenschaften

Schmelzpunkt:
>162°C (dec.)
Siedepunkt:
555.12°C (rough estimate)
Dichte
1.4216 (rough estimate)
Dampfdruck
0Pa at 25℃
Brechungsindex
1.6800 (estimate)
storage temp. 
-20°C
L?slichkeit
Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Aggregatzustand
powder
pka
3.51±0.10(Predicted)
Farbe
off-white to tan
BRN 
9238187
Stabilit?t:
We have observed that this material decomposes steadily over time. Use immediately upon receipt.
LogP
-3.685 at 25℃
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
RTECS-Nr. MA0600800
3-8-10
HS Code  2936290000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Light Tan Solid

Verwenden

Asa folic acid derivative and coenzyme, L-Tetrahydrofolic Acid can be involved in the metabolism of amino and nucleic acids.

Definition

ChEBI: A derivative of folic acid in which the pteridine ring is fully reduced; it is the parent compound of a variety of coenzymes that serve as carriers of one-carbon groups in metabolic reactions.

l?uterung methode

Very high quality material is now available commercially, and it should be a white powder. It can be dried over P2O5 in a vacuum desiccator and stored in weighed aliquots in sealed ampoules. It is stable at room temperature in sealed ampoules for many months and for much more extended periods at -10o. When moist, it is extremely sensitive to air whereby it oxidises to the yellow 7,8-dihydro derivative. In solution it turns yellow in colour as it oxidises, and then particularly in the presence of acids it turns dark reddish brown in colour. Hence aqueous solutions should be frozen immediately when not in use. It is always advisable to add 2-mercaptoethanol (if it does not interfere with the procedure for which it is used) which stabilises it by depleting the solution of O2. The sulfate salt is more stable but is much less soluble. The best way to prepare standard solutions of this acid is to dissolve it in the desired buffer and estimate the concentration by UV absorption in pH 7 buffer at 297nm ( 22,000 M-1cm-1). If a sample is suspect, it is not advisable to purify it because it is likely to deteriorate further as “dry box” conditions are necessary. Either a new sample is purchased or one is freshly prepared from folic acid. It has the above pKa values. [Hafeti et al. Biochemical Preparations 7 89 1960, UV: Mathews & Huennekens J Biol Chem 235 3304 1960, Osborn & Huennekens J Biol Chem 233 969 1958, O'Dell et al. J Am Chem Soc 69 250 1947, Blakley Biochem J 6 5 331 1957, Asahi Yakugaku Zasshi (J Pharm Soc Jpn) 79 1548 1959, Beilstein 26 III/IV 3879.]

N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 129)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29810 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 11817 58
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10319 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514
ada@ipurechemical.com CHINA 3461 58

135-16-0(N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsure)Verwandte Suche:


  • L-5,6,7,8-Tetrahydrofolic acid
  • Tetrahydropteroylglutaamic acid
  • (6S)-Thfa
  • C00101
  • Tetrahydrofolic acid,5,6,7,8-Tetrahydropteroyl-L-glutamic acid, THF
  • L-Tetrahydrofolic Acid, synthesized on receipt of order. 95% MiniMuM purity when shipped.
  • (-)-L-5,6,7,8-Tetrahydrofolic acid
  • 2-[[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
  • Tetrahydrofolic acid 5,6,7,8-Tetrahydropteroyl-L-glutamic acid
  • tetrahydrofolic acid dihydrochloride dihydrate
  • tetrahydrofolic acid sealed ampule
  • N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
  • Tetrahydrofolic acide
  • L-Tetrahydrofolic Acid
  • (2S)-2-(4-(((2-Amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
  • -2-(4-(((2-Amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)
  • Tetrahydofolic acid
  • 5,6,7,8-tetrahydrofolicacid
  • glutamicacid,n-(p-(((2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)
  • l-amino)benzoyl)
  • tetrahydropteroylglutamicacid
  • 5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID
  • N-[4-[[(2-AMino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid
  • (2S)-2-(4-(((2-aMino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)aMino)benzaMido)pentanedioic acid
  • THFA Tetrahydrofolic acid
  • Folic Acid Impurity 11
  • L-Tetrahydrofolic Acid (>
  • 70% when packaged)
  • L-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
  • L-Tetrahydrofolic Acid USP/EP/BP
  • L-Tetrahydrofolic Acid (>70% when packaged)
  • (6S)-Tetrahydrofolic acid
  • TETRAHYDROFOLIC ACID
  • Tetrahydrofolic acid 3HCL
  • L-5,6,7,8
  • (6R,S)-5,6,7,8-Tetrahydrofolic acid trihydrochloride (6R,S-FH43HCL)
  • 135-16-0
  • C19H23N7O6
  • Enzymes, Inhibitors, and Substrates
  • Cofactor
  • Cofactors
  • Metabolites and Cofactors on the Metabolic Pathways Chart
  • Metabolic Pathways
  • Metabolomics
  • Oxidation-Reduction
  • Biochemicals and Reagents
  • BioChemical
  • Folic
  • co-factor
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral Reagents
  • Elisa Kit-Mouse Elisa Kit
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