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tipepidine

tipepidine Struktur
5169-78-8
CAS-Nr.
5169-78-8
Englisch Name:
tipepidine
Synonyma:
Cr/662;At 327;Bitiodin;tipepidine;Brn 0212554;tipepidine USP/EP/BP;14698-07-8 (Citrate[1:1]);3-(Dithien-2-ylmethylene)-1-methylpiperidine;3-(Di-2-thienylmethylene)-1-methyl-piperidine;1-Methyl-3-piperidylidenedi(2-thienyl)methane
CBNumber:
CB1875368
Summenformel:
C15H17NS2
Molgewicht:
275.43
MOL-Datei:
5169-78-8.mol

tipepidine Eigenschaften

Schmelzpunkt:
64-65°
Siedepunkt:
bp4-5 178-184°
Dichte
1.1947 (rough estimate)
Brechungsindex
1.5300 (estimate)
pka
8.23±0.20(Predicted)
Aggregatzustand
Solid
Farbe
White to light yellow

Sicherheit

Toxizit?t LD50 in mice (mg/kg): 294 i.p.; 308 i.m.; 867 orally (Higaki)

tipepidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Sotal,G. Ramon

Manufacturing Process

From ethyl 1-methylpiperidine-3-carboxylate (which was prepared by hydrogenation of ethyl nicotinate with Ni-catalyst and then by methylation by action dimethyl sulfate) and 2-thienyl magnesium bromide was synthesized 1,1-di(thiophen-2-yl)-2-(3'-N-methylpiperidine), 3-(di-2-thienylmethylene)-1- methylpiperidine was obtained by dehydration of 1,1-di(thiophen-2-yl)-2-(3'- N-methylpiperidine) by action of base.

Therapeutic Function

Antitussive, Expectorant

tipepidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Dimethylsulfat Wasserstoff Nickel Ethylnicotinat

Downstream Produkte

tipepidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nanjing Gold Pharmaceutical Technology Co. Ltd. 		025-84209270 15906146951
CHINA 115 55
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338
 stella@zetchem.com China 2136 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30241 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22883 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19863 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Chengdu Feibo Pharm Technology Co., Ltd +86 028-84641798 15982321820
 abby@arkpharm.com China 10925 58
Hangzhou Dechem Tech Co.，Ltd 86-0571-87649320
dechem@aliyun.com China 162 58

5169-78-8()Verwandte Suche:

  • 14698-07-8 (Citrate[1:1])
  • 1-Methyl-3-piperidylidenedi(2-thienyl)methane
  • 3-(Di-2-thienylmethylene)-1-methyl-piperidine
  • At 327
  • Bitiodin
  • Brn 0212554
  • Cr/662
  • 3-(Dithien-2-ylmethylene)-1-methylpiperidine
  • tipepidine
  • 3-(dithiophen-2-ylmethylidene)-1-methylpiperidine
  • 3-( di-2-thienylmethylene)-1-methylpiperidine hydrochloride
  • Piperidine, 3-(di-2-thienylmethylene)-1-methyl-
  • tipepidine USP/EP/BP
  • 5169-78-8
  • C15H17NS2
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