Torasemide
|
|
|
- CAS-Nr.
- 56211-40-6
- Englisch Name:
- Torasemide
- Synonyma:
- TORSEMIDE;DEMADEX;Unat;TOREM;LUPLAC;Luprac;AC-4464;JDL-464;GJ-1090;BM-02015
- CBNumber:
- CB1397929
- Summenformel:
- C16H20N4O3S
- Molgewicht:
- 348.42
- MOL-Datei:
- 56211-40-6.mol
|
Torasemide Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36:Reizt die Augen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Torasemide is a novel loop diuretic launched in 1993 after a 12-year gap from the last
diuretic introduction. It is indicated for the treatment of hypertension and edema associated
with chronic congestive heart failure, renal disease and hepatic cirrhosis. Torasemide exerts
its major diuretic activity on the thick ascending limb of the Henle's loop to promote rapid and
marked excretion of water, Na
+, Cl
-, and to a lesser extent,K
+ and Ca
2+. Compared with other
loop diuretics such as furosemide, torasemide has a stronger antihypertensive action, a
higher bioavailability, a longer duration of action that is independent of the renal function, and
has no side effects such as paradoxical antidiuresis. The mechanism of its vasodilating effect
has been suggested to result from, at least in part, the competitive antagonism of the
thromboxane A2 receptor.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Torasemide is a loop diuretic. Diuretics have been abused as performance-enhancing drugs and masking agents in doping in sports. Use of torsemide is effective for the treatment of edema associated with chronic renal failure. The pharmacology of torasemide is similar to that of frusemide,though torasemide has a longer duration of action with a plasma half-life of approximately 3.5 hours. It also causes a less marked loss of potassiumand calcium.
Definition
ChEBI: Torasemide is an N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure. It has a role as a loop diuretic and an antihypertensive agent. It is a N-sulfonylurea, an aminopyridine and a secondary amino compound. It is functionally related to a 4-aminopyridine.
Torasemide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Torasemide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 412)Lieferanten
56211-40-6()Verwandte Suche:
- TorseMide(DeMadex)
- TorseMide API
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
Torasemide
- TroseMide
- Torasemide Tables
- N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
- JDL-464
- BM-02015
- 3-pyridinesulfonamide,n-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)am
- AC-4464
- 1-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonyl-3-propan-2-yl-urea
- LUPLAC
- N-[[(1-METHYLETHYL)AMINO]CARBONYL]-4-[(3-METHYLPHENYL)AMINO]-3-PYRIDINESULFONAMIDE
- TORADIUR
- TOREM
- TORASEMIDE
- N-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonylmethanamide
- N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide, AC-4464, BM-02015, JDL-464, Demadex, Luplac, Toradiur, Torem, Torasemide.
- TORASEMIDE(SUBJECTTOPATENTFREE)
- 3-Pyridinsulfonamid, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
- n-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfo
- TORASEMIDE,TORSEMIDE
- TorsemideUsp2598-102%
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
- 3-Pyridinesulfonamide, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
- Luprac
- GJ-1090
- N-(Isopropylaminocarbonyl)-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
- 1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea
- 1-isopropyl-3-[[4-(3-methylanilino)-3-pyridyl]sulfonyl]urea
- Torsemide (200 mg)
- 1-{4-[(3-Methylphenyl)aMino]pyridine-3-sulfonyl}-3-(propan-2-yl)urea
- Unat
- Demadex, N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
- Torsemide for System Suitability
- Torsemide (Torasemide)
- 1-[[4-(3-methylanilino)-3-pyridinyl]sulfonyl]-3-propan-2-ylurea
- TorseMide(anhydrous)
- Torasemide anhydrous CRS
- Torasemide for system suitability CRS
- Torasemide USP/EP/BP
- Torasemi
- TorsemideQ: What is
Torsemide Q: What is the CAS Number of
Torsemide Q: What is the storage condition of
Torsemide
- Torasemide Sodium
- Torsemide (1672304)
- Verbenalol β-D-glucopyranoside
- DEMADEX
- TORSEMIDE
- orasemide
- Torasemi impurity 7
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
(Torsemide Intermediate)
- Torsemide in Methanol
- 56211-40-6
- C16H20N4O3S
- ANTIZOL
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
