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Bezafibrat

Bezafibrate Struktur
41859-67-0
CAS-Nr.
41859-67-0
Bezeichnung:
Bezafibrat
Englisch Name:
Bezafibrate
Synonyma:
CEDUR;bf-759;bm15075;Befizal;Bezatol;BEZALIP;Benzabet;Difaterol;Bezabrate;Benzabate
CBNumber:
CB1188501
Summenformel:
C19H20ClNO4
Molgewicht:
361.82
MOL-Datei:
41859-67-0.mol

Bezafibrat Eigenschaften

Schmelzpunkt:
184 °C
Siedepunkt:
572.1±45.0 °C(Predicted)
Dichte
1.260±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMF: soluble
Aggregatzustand
solid
pka
3.29±0.10(Predicted)
Farbe
White to Off-White
Merck 
14,1195
Stabilit?t:
Hygroscopic
LogP
2.504 (est)
CAS Datenbank
41859-67-0(CAS DataBase Reference)
EPA chemische Informationen
Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl- (41859-67-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 22
S-S?tze: 36
WGK Germany  1
RTECS-Nr. UE8755000
HS Code  29242990
Toxizit?t LD50 oral in rat: 1082mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit

Bezafibrat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC50s = 50, 60, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively). It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 μM. Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.

Chemische Eigenschaften

Off-White Solid

Verwenden

Bezafibrate has been used:
  • a supplement in the standard diet (SD)?for mice to study its effect on diabetes
  • to evaluate its effect on hepatitis C virus (HCV) assembly and secretion
  • to evaluate its effect on gonadal steroidogenesis and?spermatogenesis?of zebrafish and also used as standard for HPLC

Bezafibrat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

4-Chlorbenzoylchlorid 4-(2-Aminoethyl)phenol Ethyl-2-brom-2-methylpropionat Natrium

Downstream Produkte

Bezafibrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 398)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085
 abby@weibangbio.com China 8806 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578
 sales@hbmojin.com China 12831 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325
 sales1@chuanghaibio.com China 5889 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618092446649
 sarah@tnjone.com China 1143 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29879 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Longyan Tianhua Biological Technology Co., Ltd 		0086 18039857276 18039857276
 CHINA 2783 58

41859-67-0(Bezafibrat)Verwandte Suche:

  • Bezafibrate D6 (dimethyl D6)
  • Bezabrate D6 (DiMethyl D6)
  • 2-(4-{2-[(4-chlorophenyl)forMaMido]ethyl}phenoxy)-2-Methylpropanoic acid
  • Bezafibrate-d6
  • BEZAFIBRATE EPB(CRM STANDARD)
  • BEZAFIBRATE MM(CRM STANDARD)
  • bezafibrat
  • bezafibrato
  • bf-759
  • bm15075
  • ([(Chloro-4-benzamido)-2-ethyl]-4-phenoxy)-2-methylpropionic acid
  • 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid
  • Befizal
  • Bezatol
  • Difaterol
  • 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid
  • 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid
  • Bezafibrate,2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
  • 2-[4-[2-(4-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPANOIC ACID
  • 2-[4-(2-[4-CHLOROBENZAMIDO]ETHYL)-PHENOXYL]-2-METHYLPROPANOIC ACID
  • 2-[4-(2-[4-CHLOROBENZOMIDO]ETHYL)-PHENOXY]-2-METHYLPROPANOIC ACID
  • 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID
  • Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-
  • Bezafibrate, 98.0%(LC&T
  • Bezafibrate Imp.(EP)
  • AURORA KA-851
  • BEZAFIBRATE
  • BEZALIP
  • CEDUR
  • 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-propionicaci
  • 2-(p-(2-(p-chlorobenzamido)ethyl)phenoxy)-2-methylpropionicacid
  • Bezafibrate 41859-67-0
  • BezafibrateQ: What is Bezafibrate Q: What is the CAS Number of Bezafibrate Q: What is the storage condition of Bezafibrate Q: What are the applications of Bezafibrate
  • Bezafibrate CRS
  • Bezafibrate >
  • Bezabrate
  • 2-[4-[2-[[(4-chlorophenyl)-oxomethyl]amino]ethyl]phenoxy]-2-methylpropanoate
  • Bezafibrate Solution, 100ppm
  • 2-(89-Chlorobenzoyl)benzoic&acid
  • N-(4-Chlorobenzoyl)-Tyramine (Bezafibrate Intermediate)
  • Benzabet
  • Bezafibrate in methanol
  • Bezafibrate 100 μg/ml Acetonitrile
  • Benzabate
  • Benzafibrate Impurity
  • Bezafibrate, Pan-PPAR agonist
  • Bezafibrate, 10 mM in DMSO
  • 41859-67-0
  • 637927-29-7
  • 1859-67-0
  • C19H20ClNO4
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Gene Regulation and Expression
  • PPAR and RXR Regulators
  • Intracellular receptor
  • Intermediates & Fine Chemicals
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