Cyclicdimethylpolysiloxane Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Cyclomethicone occurs as a clear, colorless and tasteless volatile liquid.
Verwenden
Pharmaceutic aid (wetting agent).
Vorbereitung Methode
Cyclomethicone is manufactured by the distillation of crude polydimethylsiloxanes.
Pharmazeutische Anwendungen
Cyclomethicone is mainly used in topical pharmaceutical and cosmetic formulations such as water-in-oil creams.
Cyclomethicone has been used in cosmetic formulations, at concentrations of 0.1-50%, since the late 1970s and is now the most widely used silicone in the cosmetics industry. Its high volatility, and mild solvent properties, make it ideal for use in topical formulations because its low heat of vaporization means that when applied to skin it has a ‘dry’ feel.
Sicherheit(Safety)
Cyclomethicone is generally regarded as a relatively nontoxic and nonirritant material. Although it has been used in oral pharmaceutical applications, cyclomethicone is mainly used in topical pharmaceutical formulations. It is also widely used in cosmetics. Studies of the animal and human toxicology of cyclomethicone suggest that it is nonirritant and not absorbed through the skin. Only small amounts are absorbed orally; an acute oral dose in rats produced no deaths.
Lager
Cyclomethicone should be stored in an airtight container in a cool, dry, place.
Regulatory Status
Included in the FDA Inactive Ingredients Database(oral powderfor reconstitution, topical lotion, topical cream, topical emulsion). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Cyclicdimethylpolysiloxane Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte