99105-77-8
99105-77-8 結(jié)構(gòu)式
基本信息
磺草酮
硝磺酮
磺草酮 標準品
甲醇中磺草酮溶液,100ΜG/ML
2-(2-氯-4-甲砜基)苯甲酰基-1
2-(2-氯-4-甲磺酰苯甲酰環(huán)己烷-1,3-二酮
2-(2-氯-4-甲磺酰苯甲酰)-1,3-環(huán)己二酮
2-(2-氯-4-甲砜基)苯甲?；?1,3-環(huán)己二酮
2-[2-氯-4-(甲磺酰)苯甲?；鵠-1,3-環(huán)己二酮
SC0051
GALLEON
ICIA0051
SULCOTRIONE
CHLORMESULON
Sulcotrione 0
Sulcotrione 95%
SULCOTRIONE,MESOTRIONE
Sulcotrione@100 μg/mL in Methanol
物理化學性質(zhì)
安全數(shù)據(jù)
常見問題列表
HPPD
The results show that sulcotrione behaves as time-independent reversible inhibitor. Similar results are previously described for natural β-triketones, and for the synthetic β-triketone NTBC. However it is the first time that such behavior is observed using a purified hydroxyphenylpyruvate dioxygenase (HPPD) and a synthetic β-triketone, namely sulcotrione. Inhibition kinetic analysis, performing with 3 hydroxyphenylpyruvate (HPP) and sulcotrione concentrations, show that the apparent K M increasing with sulcotrione concentration. This behavior is consistent with the data present in the literature, describing sulcotrione as a competitive inhibitor of HPPD.
大鼠急性經(jīng)口LD50>5000mg/kg。兔急性經(jīng)皮LD50>4000mg/kg。兔皮膚對其吸收率不高，對皮膚無刺激性，對兔眼中度刺激;對豚鼠皮膚強致敏性。大鼠急性吸入LC50 (4h)1.6mg/L。大鼠 NOEL 數(shù)據(jù)(2y)100mg/L[0.5mg/(kg ·d)]。ADI(EC)0.0004mg/kg[2008];(BfR)0.007mg/kg[2006]。對大鼠和兔無致畸作用，且無基因毒性。