55750-63-5
中文名稱
6-(馬來酰亞胺基)己酸琥珀酰亞胺酯
英文名稱
N-Succinimidyl 6-maleimidohexanoate
CAS
55750-63-5
分子式
C14H16N2O6
MDL 編號
MFCD00043043
分子量
308.29
MOL 文件
55750-63-5.mol
更新日期
2025/01/23 16:18:13
55750-63-5 結(jié)構(gòu)式
基本信息
中文別名
EMCS6-(馬來酰亞胺基)己酸琥珀酰亞胺酯
英文別名
6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTEREMCS
EPSILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER
N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER
N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE
N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
N-SUCCINIMIDYL-6-MALEMIDOCAPROATE, 99%
EPISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID
6-maleimidohexanoic acid n-succinimidyl ester
N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate
6-Maleimidocaproic acid N-hydroxysuccinimide ester
N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS
所屬類別
化學(xué)試劑：其他酯類化合物物理化學(xué)性質(zhì)
熔點(diǎn)70-73 °C(lit.)
沸點(diǎn)480.6±47.0 °C(Predicted)
密度1.40±0.1 g/cm3(Predicted)
儲存條件−20°C
溶解度chloroform: 100mg/mL
酸度系數(shù)(pKa)-2.21±0.20(Predicted)
形態(tài)powder
顏色灰白色至淺棕色
敏感性Light & Moisture Sensitive & Hygroscopic
BRN1499815
InChIInChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChIKeyVLARLSIGSPVYHX-UHFFFAOYSA-N
SMILESN1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
CAS 數(shù)據(jù)庫55750-63-5(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險性描述H315-H319-H335
危險品標(biāo)志Xn,Xi
危險類別碼R36/37/38-R40
安全說明S26-S36/37-S36
WGK Germany3
海關(guān)編碼29280000
常見問題列表
簡介
6-(馬來酰亞胺基)己酸琥珀酰亞胺酯是一種異雙官能團(tuán)交聯(lián)試劑，與胺和巰基反應(yīng)性的延長間隔結(jié)合。通常，最初通過pH 7.5緩沖的酰胺鍵與含有初級胺的分子耦合(6.5-8.5)，第二次耦合是通過pH 6.8緩沖的硫醚鍵與含有游離巰基的分子耦合(6.5-7.0)。
應(yīng)用
6-(馬來酰亞胺基)己酸琥珀酰亞胺酯可用于酶免疫偶聯(lián)劑和半抗原載體分子偶聯(lián)劑的制備。包含9個原子鏈接器。與芳香族間隔物相比，延長的脂肪間隔物在耦合前穩(wěn)定了馬來酰亞胺。
生物活性
6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) 是一種異雙官能團(tuán)交聯(lián)劑。EMCS 是一種制備半抗原結(jié)合物和酶免疫偶聯(lián)物的獨(dú)特而有用的試劑。靶點(diǎn)
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Non-cleavable
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體外研究
6-Maleimidohexanoic acid N-hydroxysuccinimide ester is coupled to the peptides, and then conjugated to the Adenovirus vector containing luciferase gene as adenovirus vector carrier.
6-(馬來酰亞胺基)己酸琥珀酰亞胺酯價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | H65996 | 6-馬來酰亞胺基己酸 N-丁二烯胺亞胺酯, 95% 6-Maleimidocaproic acid N-succinimidyl ester, 95% | 55750-63-5 | 250mg | 1199元 |
| 2024/11/08 | H65996 | 6-馬來酰亞胺基己酸 N-丁二烯胺亞胺酯, 95% 6-Maleimidocaproic acid N-succinimidyl ester, 95% | 55750-63-5 | 1g | 3821元 |
| 2024/11/08 | HY-78961 | 6-(馬來酰亞胺基)己酸琥珀酰亞胺酯 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | 100mg | 100元 |