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491878-07-0

中文名稱 多尼培南縮合物
英文名稱 (4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-1-[[(4-nitrophenyl)methoxy]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester
CAS 491878-07-0
分子式 C30H34N6O12S2
分子量 734.75
MOL 文件 491878-07-0.mol
更新日期 2024/10/22 10:20:54
491878-07-0 結(jié)構(gòu)式 491878-07-0 結(jié)構(gòu)式

基本信息

中文別名
多立培南縮合物
多尼培南縮合物
多尼培南聚合物雜質(zhì)
多尼培南縮合物:DORIPENEM CONDENSATION COMPOUND
英文別名
Doripenem Impurity
Doripenem condensate
Condensation Compound
Doripenem Condensation Compound
(4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-1-[[(4-nitrophenyl)methoxy]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-o
4-nitrobenzyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-[[(3S,5S)-1-(4-nitrobenzyloxycarbonyl)-5-(sulfamoylaminomethyl)pyrrolidin-3-yl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
(4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-1-[[(4-nitrophenyl)methoxy]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-1-[[(4-nitrophenyl)methoxy]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4-nitrophenyl)methyl ester, (4R,5S,6S)-
(4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-1-[[(4-nitrophenyl)methoxy]carbonyl]-3-pyrrolidinyl]thioChemicalbook]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid(4-nitrophenyl)methylester USP/EP/BP

物理化學(xué)性質(zhì)

熔點(diǎn)160-180 °C (decomp)
沸點(diǎn)950.3±75.0 °C(Predicted)
密度1.59±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)10.91±0.60(Predicted)
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