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156-28-5

中文名稱 2-苯乙胺鹽酸鹽
英文名稱 2-Phenylethylamine hydrochloride
CAS 156-28-5
EINECS 編號(hào) 205-849-2
分子式 C8H12ClN
MDL 編號(hào) MFCD00012893
分子量 157.64
MOL 文件 156-28-5.mol
更新日期 2024/10/29 16:11:18
156-28-5 結(jié)構(gòu)式 156-28-5 結(jié)構(gòu)式

基本信息

中文別名
2-苯乙胺鹽酸鹽
beta-苯乙胺鹽酸鹽
β-苯乙胺鹽酸鹽
苯乙胺鹽酸鹽Β-苯乙胺鹽酸鹽2-苯乙胺鹽酸鹽
Β-苯乙胺鹽酸鹽
英文別名
2-PHENYLETHYLAMINE HCL
2-PHENYLETHYLAMINE HYDROCHLORIDE
BETA-PHENYLETHYLAMINE HCL
BETA-PHENYLETHYLAMINE HYDROCHLORIDE
B-PHENYLETHYLAMINE HYDROCHLORIDE
PHENETHYLAMINE HYDROCHLORIDE
Phenethylammonium chloride
1-Phenyl-2-aminoethane hydrochloride
1-phenyl-2-aminoethanehydrochloride
Benzeneethanamine, hydrochloride
benzeneethanamine,hydrochloride
benzeneethanaminehydrochloride
beta-Phenethylamine hydrochloride
beta-phenethylaminehydrochloride
beta-Phenylathylaminhydrochlorid
USAF el-76
usafel-76
β-Phenylethylamine hydrochloride
B-PHENYLETHYLAMINE HCL
2-PhenylethylamineHydrochloride,99%
所屬類別
有機(jī)原料:無環(huán)單胺、多胺及其衍生物和鹽

物理化學(xué)性質(zhì)

外觀性狀白色粉末,熔點(diǎn) 220-222℃ 。
熔點(diǎn)220-222 °C(lit.)
沸點(diǎn)217 °C
閃點(diǎn)81 °C
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 10 mg/ml
形態(tài)粉末或結(jié)晶粉末
顏色白色至灰白色
Merck6026
BRN3624163
InChIInChI=1S/C8H11N.ClH/c9-7-6-8-4-2-1-3-5-8;/h1-5H,6-7,9H2;1H
InChIKeySKHIBNDAFWIOPB-UHFFFAOYSA-N
SMILESC1(CCN)=CC=CC=C1.Cl
LogP1.458 (est)
CAS 數(shù)據(jù)庫156-28-5(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息2-Phenylethylammonium chloride(156-28-5)
EPA化學(xué)物質(zhì)信息Benzeneethanamine, hydrochloride (156-28-5)

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
危險(xiǎn)品標(biāo)志Xn,Xi
危險(xiǎn)類別碼R22-R36/37/38
安全說明S26-S36
危險(xiǎn)品運(yùn)輸編號(hào)2811
WGK Germany3
RTECS號(hào)SH7175000
危險(xiǎn)等級(jí)6.1(b)
包裝類別III
毒性eye-man 50 mg SEV AIMDAP 39,404,27

常見問題列表

應(yīng)用
2-苯乙胺鹽酸鹽是一種伯胺類化合物。2-苯乙胺鹽酸鹽是一類重要的化工原料,在化學(xué)工業(yè)(尤其是精細(xì)化工和醫(yī)藥工業(yè)) 領(lǐng)域有著廣泛的用途。
制備

(1)酰亞胺化:將3,4-二苯基呋喃-2,5-二酮(100.0mg,0.4mmol)、1%氨水(3.4g, 2.0mmol)加入到10mL微波反應(yīng)管中,設(shè)定微波反應(yīng)器的功率為80W,在120℃下微波輻射反 應(yīng)5分鐘;待冷卻后,使用20mL乙酸乙酯萃取兩次,合并有機(jī)層,加入無水硫酸鈉干燥,減壓 下回收溶劑乙酸乙酯,得3,4-二苯基-1H-吡咯-2,5-二酮,收率100%,直接用于后續(xù)的N-烴基化反應(yīng)。

(2)N-烴基化:加入β-溴苯乙烷(73.6mg,0.4mmol),得到1-苯乙基-3,4-二苯基- 1H-吡咯-2,5-二酮。

(3)水解:上述1-苯乙基-3,4-二苯基-1H-吡咯-2,5-二酮水解,得到原料3,4-二苯 基呋喃-2,5-二酮(97.6mg),回收率為98%;得到2-苯乙胺鹽酸鹽(56.6mg),收率90%。(以 原料β-溴苯乙烷計(jì))。
生物活性
2-Phenylethanamine hydrochloride 被認(rèn)為是一種神經(jīng)調(diào)節(jié)劑或神經(jīng)遞質(zhì)。
體外研究

2-Phenylethanamine (PEA) is soluble in water, ethanol, and ether. Phenethylamine is a skin irritant and possible sensitizer. 2-Phenylethanamine is believed to function as a neuromodulator or neurotransmitter (a trace amine). It is also found in many foods such as chocolate, especially after microbial fermentation. 2-Phenylethanamine is a precursor to the neurotransmitter phenylethanolamine. High levels of 2-Phenylethanamine have been found in the urine of schizophrenics but it is not significantly elevated in the serum or CSF of schizophrenics. Urinary levels of 2-Phenylethanamine are significantly lower in children with attention deficit hyperactivity disorder. 2-Phenylethanamine is useful for scaring off rodent pests.

2-苯乙胺鹽酸鹽價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/08/19441912-苯乙胺鹽酸鹽 25GR
2-Phenylethylamine hydrochloride, 98%, Thermo Scientific Chemicals
156-28-525g1128元
2024/08/19S53462-苯乙胺鹽酸鹽
2-Phenylethylamine hydrochloride
156-28-525mg795.24元
2024/04/30C441912-苯乙胺鹽酸鹽 25GR
2-Phenylethylamine hydrochloride, 98%
156-28-525g1128元
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