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106461-41-0

中文名稱 2,4-二氫-4-[[4-(4-羥基苯基)-1-哌嗪基]苯基]-2-(1-甲基丙基)-3H-1,2,4-三氮唑-3-酮
英文名稱 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
CAS 106461-41-0
分子式 C22H27N5O2
MDL 編號 MFCD02093087
分子量 393.48
MOL 文件 106461-41-0.mol
更新日期 2024/12/19 11:11:38
106461-41-0 結(jié)構(gòu)式 106461-41-0 結(jié)構(gòu)式

基本信息

中文別名
2,4-二氯-4-(4-(4-羥基苯基)-1-哌嗪基)-苯基)-2-(1-甲基丙基)-3H-1,2,4-三氮唑-3-酮
三氮唑酮
2,4-二氫-4-[[4-(4-羥基苯基)-1-哌嗪基]苯基]-2-(1-甲基丙基)-3H-1,2,4-三氮唑-3-酮
英文別名
1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE
2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOL-3-ONE
2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
2,4-DIHYDRO-4-[4-(4-HYDROXYPHENYL)1-PIPERAZINYLPHENYL]-2-(1-METHYL-PROPYL)-3H-1,2,4-TRIAZOL-3-ONE
2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
2-SEC-BUTYL-4-[4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL]-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
2-sec-butyl-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2h-1,2,4-triazol-3(4h)-one
2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-3
2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-3h-1,2,4-Triazol-3-One
Dhmt
2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one(DHMT)
2,4-Dihydro-4[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]-Phenyl]-2-(1-Methylpropyl)-3H-1,Triazole-3-One
2,4-Dihydro-4-[4-[4-(4-Hydroxylphenyl)Piperazin-l-ylPhenyl-2-(l-Methylpropyl)-3H-1,2,4-Triazol-3-One
2,4-Dichloro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl]-phen-yl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
2,4-Dihydro-4-{4-Hydroxyphenyl)-2-(1- Methyl Propyl)-3H-1,2,4-Triazole-3-One
2,4-dihydro-4-[4-[4-4-(hydroxyphenyl)-1-
piperazinyl]phenyl]-2-(1-methylpropyl)-
所屬類別
醫(yī)藥中間體:雜環(huán)化合物

物理化學(xué)性質(zhì)

熔點(diǎn)177-179°C
沸點(diǎn)587.9±60.0 °C(Predicted)
密度1.25±0.1 g/cm3(Predicted)
儲(chǔ)存條件Sealed in dry,Room Temperature
溶解度可溶于氯仿(少許)、乙酸乙酯(少許)、甲醇(少許)
酸度系數(shù)(pKa)12.18±0.30(Predicted)
形態(tài)固體
顏色灰白色淺棕色
CAS 數(shù)據(jù)庫106461-41-0(CAS DataBase Reference)

安全數(shù)據(jù)

危險(xiǎn)性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335

應(yīng)用領(lǐng)域

用途一
伊曲康唑合成的中間體。

常見問題列表

應(yīng)用

2,4-二氫-4-[[4-(4-羥基苯基)-1-哌嗪基]苯基]-2-(1-甲基丙基)-3H-1,2,4-三氮唑-3-酮可作為有機(jī)合成中間體和醫(yī)藥中間體,主要用于實(shí)驗(yàn)室研發(fā)過程和化工生產(chǎn)過程中,主要用于原料藥伊曲康唑的合成。

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