| Identification | More | [Name]
Bromoacetic acid | [CAS]
79-08-3 | [Synonyms]
2-BROMOACETIC ACID
alpha-Bromoacetic acid
BROMOACETIC ACID
BROMOACETIC ACID IN ETHYLENEGLYCOL
MBA
MONOBROMOACETIC ACID
RARECHEM AL BO 0099
Aceticacid,bromo-
Acide bromacetique
acidebromacetique
alpha-Bromoethanoic acid
alpha-bromoethanoicacid
Bromaceticacid
bromoacetateion
bromoacetic
bromo-aceticaci
bromoaceticacid,solution
Bromoethanoic acid
bromoethanoicacid
CH2BrCOOH | [EINECS(EC#)]
201-175-8 | [Molecular Formula]
C2H3BrO2 | [MDL Number]
MFCD00002678 | [Molecular Weight]
138.95 | [MOL File]
79-08-3.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO LIGHT YELLOW CRYSTALLINE MASS | [Melting point ]
46-49 °C
| [Boiling point ]
208 °C(lit.)
| [density ]
1
| [vapor pressure ]
1 mm Hg @ 550C | [refractive index ]
1.4804 (estimate) | [Fp ]
>110°C | [storage temp. ]
0-6°C
| [solubility ]
chloroform: soluble10%, clear, colorless | [form ]
Crystalline Mass or Crystalline Powder, Flakes, Crystals and/or Chunks | [pka]
2.69(at 25℃) | [color ]
White to yellow | [Water Solubility ]
miscible | [Sensitive ]
Light Sensitive & Hygroscopic | [Merck ]
14,1400 | [BRN ]
506167 | [Uses]
Organic synthesis, abscission of citrus fruit in
harvesting.
| [CAS DataBase Reference]
79-08-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetic acid, bromo-(79-08-3) | [EPA Substance Registry System]
79-08-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,C,N,Xi,F | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R35:Causes severe burns.
R50:Very Toxic to aquatic organisms.
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36:Wear suitable protective clothing .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3425 8/PG 2
| [WGK Germany ]
2
| [RTECS ]
AF5950000
| [F ]
3-19-23 | [Hazard Note ]
Toxic/Corrosive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29159000 | [Safety Profile]
Poison by ingestion,
intraperitoneal, and intravenous routes.
Irritating and corrosive to skin and mucous
membranes. Mutation data reported. When
heated to decomposition it emits toxic
fumes of Br-. See also BROMIDES. | [Hazardous Substances Data]
79-08-3(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Aqueous solution. | [Reactivity Profile]
Carboxylic acids, such as BROMOACETIC ACID, donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in BROMOACETIC ACID, SOLUTION(79-08-3) to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. | [Air & Water Reactions]
Water soluble. | [Hazard]
Strong irritant to skin and tissue.
| [Health Hazard]
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | [Fire Hazard]
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. | [Chemical Properties]
WHITE TO LIGHT YELLOW CRYSTALLINE MASS | [Flammability and Explosibility]
Nonflammable | [Purification Methods]
Crystallise bromoacetic acid from pet ether (b 40-60o). A diethyl ether solution of it is passed through an alumina column, and the ether is evaporated at room temperature under vacuum. It is best obtained by distillation from a Claisen (flask immersed in an oil bath) fitted with an insulated Vigreux column (p 11) and the fraction b 108-110o/30mm is collected. It is light and moisture sensitive. [Natelson & Gottfried Org Synth Coll Vol III 381 1955, Beilstein 2 IV 526.] LACHRYMATORY and is a skin IRRITANT. |
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