| Identification | More | [Name]
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride | [CAS]
637-01-4 | [Synonyms]
N,N,N',N'-TETRAMETHYL-1,4-BENZENEDIAMINE, DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMINE DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMMONIUM DICHLORIDE
N,N,N',N'-TETRAMETHYL-4-PHENYLENEDIAMINE DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE 2HCL
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE DI HCL
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE DIHYDROCHLORIDE
TMPD
TMPD DIHYDROCHLORIDE
WURSTER-REAGENT
WURSTER'S REAGENT
WURSTER'S REAGENT DIHYDROCHLORIDE
1,4-Benzenediamine,N,N,N’,N’-tetramethyl-,dihydrochloride
4-benzenediamine,n,n,n’,n’-tetramethyl-dihydrochloride
n,n,ni,ni-tetramethyl-p-phenylenediaminedihydrochloride
p-phenylenediamine,n,n,n’,n’,tetramethyl-,dihydrochloride
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
NNN'N'-Tetramethyl-p-phenylene-diamine dihydrochloride
N,N,N',N'-Tetramethyl-p-phenylenediammonium dichloride
N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E DIHYDROCH
N,NnTetramethyl-P-Phenylenediamine | [EINECS(EC#)]
211-274-8 | [Molecular Formula]
C10H18Cl2N2 | [MDL Number]
MFCD00012482 | [Molecular Weight]
237.17 | [MOL File]
637-01-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Off white to gray powder | [Melting point ]
222-224 °C(lit.) | [Boiling point ]
378.54°C (rough estimate) | [density ]
1.1961 (rough estimate) | [refractive index ]
1.6400 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble500mg/10 mL | [form ]
powder
| [color ]
off-white to gray
| [Stability:]
Stable. Incompatible with strong oxidizing agents, strong bases. | [Water Solubility ]
SOLUBLE | [Sensitive ]
Light Sensitive | [BRN ]
5132096 | [CAS DataBase Reference]
637-01-4(CAS DataBase Reference) | [EPA Substance Registry System]
637-01-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37:Wear suitable protective clothing and gloves .
S22:Do not breathe dust . | [RIDADR ]
2811 | [WGK Germany ]
3
| [F ]
8 | [TSCA ]
Yes | [HazardClass ]
6.1(a) | [PackingGroup ]
II | [HS Code ]
29215190 |
| Hazard Information | Back Directory | [Chemical Properties]
Off white to gray powder | [Uses]
N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride has been used to determine the oxidase activity displayed by various microorganisms. | [Uses]
An oxidizable compound | [Uses]
N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels. | [General Description]
N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is a redox mediator used in the oxidase test for detecting bacterial cytochrome c oxidases. TMPD is commonly used to perform the oxidase test for the colorimetric identification of pathogenic and non-pathogenic bacteria. | [Purification Methods]
Crystallise the salt from isopropyl or n-butyl alcohols, saturated with HCl. Treat it with aqueous NaOH to give the free base (see previous entry) which is filtered, dried and sublimed in a vacuum. [Guarr et al. J Am Chem Soc 107 5104 1985, Beilstein 13 H 74.] |
| Spectrum Detail | Back Directory | [Spectrum Detail]
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)MS
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)1HNMR
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)IR1
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)IR2
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