| Identification | More | [Name]
1-Methylpyrrolidine | [CAS]
120-94-5 | [Synonyms]
1-METHYLPYRROLIDINE
N-METHYLPYRROLIDINE
1-methyl
1-methyl-pyrrolidin
Methylpyrrolidine
methylpyrrolidine(non-specificname)
N-Methyltetrahydropyrrole
Pyrrolidine, N-methyl
Pyrrolidine,1-methyl-
Pyrrolidine,l-methyl- | [EINECS(EC#)]
204-438-5 | [Molecular Formula]
C5H11N | [MDL Number]
MFCD00003173 | [Molecular Weight]
85.15 | [MOL File]
120-94-5.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Melting point ]
-90 °C
| [Boiling point ]
76-80 °C (lit.) | [density ]
0.819 g/mL at 25 °C(lit.)
| [vapor pressure ]
100 hPa (20 °C) | [refractive index ]
n20/D 1.425
| [Fp ]
−7 °F
| [storage temp. ]
Flammables area | [solubility ]
213g/l | [form ]
Liquid | [pka]
10.32(at 25℃) | [color ]
Clear colorless | [PH]
11.3 (1g/l, H2O) | [explosive limit]
1.1-9.1%(V) | [Water Solubility ]
fully miscible | [Detection Methods]
GC | [BRN ]
102445 | [InChIKey]
AVFZOVWCLRSYKC-UHFFFAOYSA-N | [LogP]
1.1 at 23℃ | [CAS DataBase Reference]
120-94-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyrrolidine, 1-methyl-(120-94-5) | [EPA Substance Registry System]
120-94-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,C,N | [Risk Statements ]
R11:Highly Flammable.
R22:Harmful if swallowed.
R34:Causes burns.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R35:Causes severe burns.
R20/22:Harmful by inhalation and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S29:Do not empty into drains . | [RIDADR ]
UN 2924 3/PG 2
| [WGK Germany ]
2
| [RTECS ]
UY1420500
| [Autoignition Temperature]
170 °C DIN 51794 | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29339900 | [Safety Profile]
Poison by
intraperitoneal and intravenous routes. This
material is strongly alkaline. Liquid and
vapors are corrosive to the skin, eyes, or
mucous membranes. A very dangerous fire
hazard; keep away from sparks, heat
sources, and powerful oxidizers. Keep in
closed containers. To fight fire, use alcohol
foam. When heated to decomposition it
emits highly toxic fumes of NOx. | [Toxicity]
LD50 orally in Rabbit: 280 mg/kg |
| Hazard Information | Back Directory | [Hazard]
Flammable, dangerous fire risk. Irritant toskin and eyes. | [Chemical Properties]
CLEAR COLOURLESS LIQUID | [Uses]
A methylated pyrollidine which is an essential part of the structure of Cefipime (C242750) often analyzed via ion chromatography. A cigarette smoke constitutent. | [Preparation]
n-methylpyrrolidine was successfully synthesized in an aqueous medium by using methylamine and 1,4-dibromobutane in the presence of catalyst k2co3 at a moderated temperature. here, n-methylpyrrolidine was firstly synthesized via the green chemistry process, in which both the water solvent and potassium carbonate catalyst were inexpensive and environmentally friendly. also, the reaction temperature was quite moderated at 90°C.
green organic synthesis of n-methylpyrrolidine | [Flammability and Explosibility]
Highlyflammable | [Synthesis]
1-Methylpyrrolidine is prepared by hydrogenation of N-Methylpyrrole
over Adams' catalyst. | [storage]
Store at -20°C |
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