| Identification | More | [Name]
2-Methyl-5-nitrobenzenesulfonamide | [CAS]
6269-91-6 | [Synonyms]
2-METHYL-5-NITROBENZENESULFONAMIDE
2-METHYL-5-NITROBENZENESULPHONAMIDE
BUTTPARK 52\04-61
IFLAB-BB F1084-0158
4-Nitro-2-toluenesulfonamide
BENZENESULFONAMIDE,2-METHYL-5-NITRO-
2-methyl-5-nitrobenzene-1-sulfonamide
2-Methyl-5-nitro-1-benzenesulfonamide | [EINECS(EC#)]
220-358-3 | [Molecular Formula]
C7H8N2O4S | [MDL Number]
MFCD00115503 | [Molecular Weight]
216.21 | [MOL File]
6269-91-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
197-199 | [Boiling point ]
431.4±55.0 °C(Predicted) | [density ]
1.475±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Solid | [pka]
9.56±0.60(Predicted) | [color ]
Yellow to Dark Yellow | [CAS DataBase Reference]
6269-91-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
2-Methyl-5-nitrobenzenesulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. | [structure and hydrogen bonding]
In the 2-Methyl-5-nitrobenzenesulfonamide, C7H8N2O4S, the nitro group is twisted by 9.61 (2)° relative to the benzene ring. In the crystal, mol-ecules are linked by N—H…O and N—H…(O, O) hydrogen bonds between the amino and sulfonyl groups, forming layers parallel to (001)[1].
 | [References]
[1] Muhammad Zia-Ur-Rehman. “2-Methyl-5-nitro-benzene-sulfonamide.” Acta crystallographica. Section E, Structure reports online 66 Pt 1 (2009): o136.
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