| Identification | More | [Name]
Methylhydrazine | [CAS]
60-34-4 | [Synonyms]
MONOMETHYL HYDRAZINE
1-Methylhydrazine
CH3NHNH2
HydraZine,methyl-
Hydrazinomethane
Hydrazomethane
methyl-hydrazin
Metylohydrazyna
metylohydrazyna(polish)
MMH
Rcra waste number P068
rcrawastenumberp068
MethylHydrazine40%
METHYLHYDRAZINE (controlled chemical)
Methylydrazine
N-METHYLHYDRAZINE
Monomethyl hydrazine (MMH)
2-Methylhydrazine | [EINECS(EC#)]
200-471-4 | [Molecular Formula]
CH6N2 | [MDL Number]
MFCD00007621 | [Molecular Weight]
46.07 | [MOL File]
60-34-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Methyl hydrazine is a fuming, colorless liquid
with an ammonia-like odor. The odor threshold is
1.31.7 ppm. | [Melting point ]
-21 °C | [Boiling point ]
88-90 °C(lit.) | [density ]
0.875 g/mL at 20 °C(lit.)
| [vapor density ]
1.6 (vs air)
| [vapor pressure ]
37.5 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.4325(lit.)
| [Fp ]
70 °F
| [storage temp. ]
Flammables area | [solubility ]
Soluble in alcohol and ether (Weast, 1986) | [form ]
liquid | [pka]
8.84±0.70(Predicted) | [color ]
colorless to pale yellow | [Stability:]
Stable. Flammable. Hygroscopic. Incompatible with strong oxidizing agents, copper, iron and their alloys. | [explosive limit]
97% | [Water Solubility ]
soluble | [Merck ]
13,6109 | [BRN ]
635645 | [Exposure limits]
Potential occupational carcinogen. NIOSH REL: 2-h ceiling 0.04 ppm (0.08
mg/m3), IDLH 20 ppm; OSHA PEL: ceiling 0.2 ppm (0.35 mg/m3); ACGIH TLV: TWA 0.01 ppm
(adopted). | [Uses]
Missile propellant, intermediate, solvent. | [CAS DataBase Reference]
60-34-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Hydrazine, methyl-(60-34-4) | [EPA Substance Registry System]
60-34-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,T+,N,T | [Risk Statements ]
R11:Highly Flammable.
R24/25:Toxic in contact with skin and if swallowed .
R26:Very Toxic by inhalation.
R34:Causes burns.
R40:Limited evidence of a carcinogenic effect.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R45:May cause cancer.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S53:Avoid exposure-obtain special instruction before use .
S24/25:Avoid contact with skin and eyes . | [OEL]
Ceiling: 0.04 ppm (0.08 mg/m3) [2-hr] | [RIDADR ]
UN 1244 6.1/PG 1
| [WGK Germany ]
3
| [RTECS ]
MV5600000
| [Autoignition Temperature]
385 °F | [HazardClass ]
6.1(a) | [PackingGroup ]
I | [HS Code ]
29280000 | [Safety Profile]
Suspected carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by inhalation, ingestion, skin
contact, intraperitoneal, subcutaneous, and
intravenous routes. Experimental
reproductive effects. Human mutation data
reported. Corrosive to skin, eyes and mucous membranes. May self-ignite in air.
Very dangerous fire hazard when exposed
to heat or flame. To fight fire, use alcohol
foam, CO2, dry chemical. Explosive in the
form of vapor when exposed to heat or
flame. A powerful reducing agent. It is
hypergolic with many oxidants (e.g.,
dinitrogen tetraoxide and hydrogen
peroxide). When heated to decomposition it
emits toxic fumes of NOx. | [Hazardous Substances Data]
60-34-4(Hazardous Substances Data) | [Toxicity]
LD50 orally in mice, rats: 33.0, 32.5 mg/kg (Witkin); orally in rats: 70.7 mg/kg (Gregory) | [IDLA]
20 ppm |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Sodium hydroxide-->Ammonia-->Chlorine-->Dimethyl sulfate-->Methylamine-->Chloramine-T-->Methylhydrazine sulfate-->BENZALDEHYDE AZINE | [Preparation Products]
5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-AMINE-->1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-->4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID-->1-METHYL-3-PHENYL-1H-PYRAZOLE-5-CARBALDEHYDE-->1-METHYL-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER-->4-BROMO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-->Procarbazine hydrochloride-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBALDEHYDE-->1,5-DIMETHYL-1H-PYRAZOLE-3-CARBONYL CHLORIDE-->Antipyrine-->4-Bromo-1,3,5-trimethyl-1H-pyrazole-->1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID-->1-METHYL-5-(1H-PYRROL-1-YL)-1H-PYRAZOLE-4-CARBOXYLIC ACID-->1,3,5-Trimethylpyrazole-->1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID-->ETHYL 1-METHYL-5-(1H-PYRROL-1-YL)-1H-PYRAZOLE-4-CARBOXYLATE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONITRILE-->ETHYL 2-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE-->1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID-->1-Methyl-5-propyl-1H-pyrazole-3-carboxylic acid amide ,97%-->1-Methyl-3-propyl-1H-pyrazole-5-carboxamide ,97%-->1-Methyl-3-propyl-1H-pyrazole-5-carbohydrazide ,97%-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANOL-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE-->Azimsulfuron-->1,3-DIMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID-->1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID-->ETHYL 1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLATE-->3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER-->1,4,6-Trimethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine ,97%-->1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLIC ACID-->5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde |
| Hazard Information | Back Directory | [Reactivity Profile]
METHYLHYDRAZINE is a powerful reducing agent. Ignites upon contact with oxidizing agents i.e. dinitrogen tetraoxide, hydrogen peroxide [Hawley]. Water used to extinguish a fire may cause pollution and should be diked for later disposal. Gives basic solutions with water that generate heat when water is added. | [Air & Water Reactions]
Highly flammable. Often ignites spontaneously. Exposure to air on a large surface may result in spontaneous ignition [Def. Res. and Eng. 27. 1963]. Water soluble. Solutions are highly alkaline and generate heat when water is added. | [Hazard]
Flammable, dangerous fire risk, vapors mayexplode, may self-ignite in air and on contact withoxidizing agents. Toxic by ingestion and inhalation.Eye and upper respiratory tract irritant, lung cancerand liver damage. Possible carcinogen. | [Health Hazard]
Methyl hydrazine vapors are extremely toxic and the liquid is corrosive to skin. Methyl hydrazine is the strongest convulsant and the most toxic of methyl-substituted hydrazine derivatives. It is more toxic than hydrazine. At high doses, it is a strong central nervous system poison that can lead to convulsions and death. Skin rash may be aggravated by skin exposure. | [Potential Exposure]
MMH has been used as the propellant
in liquid propellant rockets; it is also used as a solvent and
as an organic intermediate. | [Fire Hazard]
Extremely flammable; ignites spontaneously under almost all normal temperature conditions. Water used to extinguish a fire may cause pollution and should be diked for later disposal. Water may be ineffective in extinguishing fires due to the chemical's low flash point. Because of the wide flammability limits, low flash point, and reignition hazard, dry chemicals, carbon dioxide, water spray, and foam may not be as effective as water dilution of fire area. The vapor is heavier than air; thus METHYLHYDRAZINE may accumulate sufficiently to flash back. Methylhydrazine fires produce irritating nitrogen oxides. Ignites spontaneously in air when in contact with porous materials (e.g., earth, asbestos, wood, or cloth). Also ignites spontaneously on contact with strong oxidizing agents (e.g., fluorine, chlorine trifluoride, fuming nitric acid, and nitrogen tetroxide). Heat or flame should be avoided because chemical is extremely flammable and explosive. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water or
milk. Do not induce vomiting. Medical observation is
recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for
pulmonary edema, a doctor or authorized paramedic may
consider administering a drug or other inhalation therapy.
| [Shipping]
UN1244 Methylhydrazine, Hazard class: 6.1;
Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid,
8-Corrosive material, Inhalation Hazard Zone A
| [Incompatibilities]
May form explosive mixture with air.
Methyl hydrazine is a highly reactive reducing agent and a
medium strong base. May explode if heated. Violent reaction with strong oxidizers, such as fluorine, chlorine, combustibles, nitric acid; hydrogen peroxide. Incompatible with
acids, alcohols, glycols, isocyanates, phenols, cresols;
porous materials, such as earth, asbestos, wood and cloth.
Oxides of iron or copper, manganese, lead, copper or their
alloys can lead to fire and explosions. Attacks cork, some
plastics, coatings and rubber. | [Description]
Methyl hydrazine, CH3NHNH2, is a colorless, hygroscopic liquid with an ammonia-like odor. It is soluble in water, with a specific gravity of 0.87, which is lighter than water. Methyl hydrazine is toxic by inhalation and ingestion, and is a suspected human carcinogen. The TLV ceiling is 0.2 ppm in air, and the IDLH is 50 ppm. The target organs are the central nervous system, respiratory system, liver, blood, eyes, and cardiovascular system. The four-digit UN identification number is 1244. The NFPA 704 designation is health 4, flammability 3, and reactivity 2. The primary uses are as a missile propellant and a solvent. | [Chemical Properties]
colourless liquid with an ammonia-like odour | [Chemical Properties]
Methyl hydrazine is a fuming, colorless liquid
with an ammonia-like odor. The odor threshold is
1.31.7 ppm. | [Waste Disposal]
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations
governing storage, transportation, treatment, and waste
disposal. There are 2 alternatives: Dilute with water,
neutralize with sulfuric acid, then flush to sewer with
large volumes of water or incinerate with added flammable solvent in furnace equipped with afterburner and
alkaline scrubber. | [Physical properties]
Fuming, clear, colorless liquid with an ammonia-like odor. Odor threshold concentrations ranged
from 1 to 3 ppm (quoted, Keith and Walters, 1992). | [Production Methods]
Methylhydrazine ignites spontaneously on contact with
strong oxidizing agents. It is prepared commercially from
the reaction of monochloroamine and monomethylamine. | [Carcinogenicity]
The carcinogenicity of methylhydrazine
has been extensively investigated. In two studies,
no compound-related increase in tumor incidence was
observed in mice treated orally with methylhydrazine
. In other studies, methylhydrazine produced
lung tumors in mice and malignant histiocytoma of the liver
and cecal tumors in hamsters when administered in drinking
water at concentrations of 0.01%. Potential carcinogenicity
from vapor exposure to methylhydrazine was also
investigated in rats, dogs, hamsters, and mice. Exposures to
methylhydrazine at concentrations of 0.02 ppm (rats and
mice only) and 0.2, 2, and 5 ppm (rats and hamsters only)were conducted for 6 h/day, 5 days/week, for a year, followed
by observation for 1 year. | [Source]
Rocket fuel; solvent; intermediate; organic synthesis. | [Environmental Fate]
Biological. It was suggested that the rapid disappearance of methylhydrazine in sterile and
nonsterile soil (Arrendondo fine sand) under aerobic conditions was due to chemical oxidation.
Although the oxidation product was not identified, it biodegraded to carbon dioxide in the
nonsterile soil. The oxidation product did not degrade in the sterile soil (Ou and Street, 1988). | [storage]
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trainedon its proper handling and storage. Before entering confinedspace where this chemical may be present, check to makesure that an explosive concentration does not exist. Methylhydrazine must be stored to avoid contact with oxides ofiron and copper; manganese, lead, and copper alloys;porous materials (such as earth, asbestos, wood, and cloth);oxidizers (such as perchlorates, hydrogen peroxide, chlorates, nitrates, permanganates); and fuming nitric acid sinceviolent reactions occur. Store in tightly closed containers ina cool, well-ventilated area away from heat and sparks.Sources of ignition, such as smoking and open flames, areprohibited where methyl hydrazine is handled, used, orstored. Metal containers involving the transfer of 5 gallonsor more of methyl hydrazine should be grounded andbonded. Drums must be equipped with self-closing valves,pressure vacuum bungs, and flame arresters. Use only nonsparking tools and equipment, especially when opening andclosing containers of methyl hydrazine. Wherever methylhydrazine is used, handled, manufactured, or stored, useexplosion-proof electrical equipment and fittings. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHAStandard 1910.1045. | [Purification Methods]
Dry with BaO, then distil it in a vacuum. Store it under nitrogen. [Beilstein 4 IV 3322.] | [Toxics Screening Level]
The initial risk screening level (IRSL) for methyl hydrazine is 0.0087 μg/m3 (annual). The initial threshold screening level (ITSL) is 0.03 μg/m3 (24-hour). |
|