| Identification | More | [Name]
3,3'-DITHIODIPROPIONIC ACID DI(N-SUCCINIMIDYL ESTER) | [CAS]
57757-57-0 | [Synonyms]
3,3'-DITHIO-BIS(PROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER)
3,3'-DITHIOBIS(SUCCINIMIDYL PROPIONATE)
3,3'-DITHIODIPROPIONIC ACID BIS(N-SUCCINIMIDYL ESTER)
3,3'-DITHIODIPROPIONIC ACID DI-(N-HYDROXY-SUCCINIMIDE ESTER)
3,3'-DITHIODIPROPIONIC ACID DI(N-SUCCINIMIDYL ESTER)
3,3'-DITHIOPROPIONIC ACID DI(N-SUCCINIMIDYL ESTER)
DI(N-SUCCINIMIDYL) 3,3'-DITHIODIPROPIONATE
(DISULFOSUCCINIMIDYL)SUBERATE
DITHIOBIS(SUCCINIMIDYL PROPIONATE)
DSP
DSS, WATER-SOLUBLE
DTSP
LOMANTS REAGENT
LOMANT'S REAGENT
SULFO-DSS
3,3-dithio-bis(propionic acid N-*hydroxysuccinim
disuccinimido dithiobispropionate
3,3'-DITHIO-BIS(PROPIONIC ACID N-HYDROXY SUCCINIMID
3,3-DITHIODIPROPIONIC ACID DI(N-SUCCINIMIDYL ESTER)[CROSS-LINKING REAGENT] 98+%
Dithio-bis-succinimidyl propionate (Lomant''s Reagent) | [EINECS(EC#)]
260-931-5 | [Molecular Formula]
C14H16N2O8S2 | [MDL Number]
MFCD00042045 | [Molecular Weight]
404.42 | [MOL File]
57757-57-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10-21 | [HS Code ]
29309090 |
| Hazard Information | Back Directory | [Description]
DSP Crosslinker is a cleavable crosslinker. It contains two terminal NHS ester moieties which can react with primary amines. The disulfide bonds can be cleaved via a reduction reaction using Dithiothreitol (DTT) reagent. | [Chemical Properties]
Off-White Solid | [Uses]
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker. | [Uses]
3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) can be used as amine reactive homobifunctional cross-linking reagent, cleavable under mild conditions with hydroxylamine (pH 8.5, 3-6 h, 37oC)
| [Uses]
3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) can be used in the crosslinking of intracellular proteins prior to cell lysis.
| [General Description]
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). |
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