| Identification | More | [Name]
Coelenteramine | [CAS]
55779-48-1 | [Synonyms]
2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMIDAZO [1,2-A] PYRAZIN-3-(7H)-ONE
2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZINE-3-(7H)-ONE
2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYL-IMIDAZOL[1,2-A]PYRAZIN-3-(7H)-ONE
3,2-DIHYDRO-2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZOLO[1,2-A]PYRAZIN-3-ONE
8-BENZYL-2-(4-HYDROXYBENZYL)-6-(4-HYDROXYPHENYL)IMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE
CLZ-N
CLZN-N
Coelenteramine
COELENTERAZINE
COELENTERAZINE N
COELENTERAZINE, NATIVE
COELENTERAZINE-N, SYNTHETIC
COELENTERAZIN N
H COELENTERATE LUCIFERIN
NATIVE COELENTERATE LUCIFERIN
Coelenterazine luiferin
Luciferin, Preluciferin, | [Molecular Formula]
C26H21N3O3 | [MDL Number]
MFCD00467176 | [Molecular Weight]
423.46 | [MOL File]
55779-48-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Yellow Solid | [Melting point ]
176–181 ℃ (decompose) | [Boiling point ]
641.4±65.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
methanol and ethanol: soluble
| [form ]
solid
| [pka]
9.91±0.15(Predicted) | [color ]
yellow
| [Sensitive ]
Moisture & Light Sensitive | [Usage]
A luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range | [λmax]
429nm | [Biological Applications]
Calciumindicator; detecting luciferase,protease,gene expression,nucleic acids,proteins,stem cells,quantum dot conjugates,superoxide; tracing protein dynamics; as a substrate for luciferase,alka | [InChIKey]
YHIPILPTUVMWQT-UHFFFAOYSA-N | [CAS DataBase Reference]
55779-48-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
Coelenterazine is a luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range.
| [Definition]
ChEBI: An imidazopyrazine that is imidazo[1,2-a]pyrazin-3(7H)-one in which positions 2, 6, and 8 are substituted by 4-hydroxybenzyl, 4-hydroxyphenyl, and benzyl groups, respectively. | [General Description]
Coelenterazine is a luciferin molecule, which is utilized by several luciferases, such as Renilla,?Oplophorus and?Periphylla. | [Biochem/physiol Actions]
Luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465 nm when Ca2+ binds to the complex; used to measure Ca2+ concentration in cells with high sensitivity and large dynamic range. |
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