Identification | Back Directory | [Name]
COELENTERAZINE HCP | [CAS]
123437-32-1 | [Synonyms]
CLZ-HCP CLZN-HCP COELENTERAZINE HCP Coelenterazine hcp solid COELENTERAZINE-HCP, SYNTHETIC CLZN hcp [Coelenterazine hcp] Coelenterazine hcp *CAS 123437-32-1* Coelenterazine hcp *UltraPure grade* 2-BENZYL-6-(P-HYDROXYPHENYL)-8-CYCLOPENTYLMETHYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE 2-benzyl-8-(cyclopentylmethyl)-6-(4-hydroxyphenyl)-7H-imidazo[1,2-a]pyrazin-3-one IMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE, 8-(CYCLOPENTYLMETHYL)-6-(4-HYDROXYPHENYL)-2-(PHENYLMETHYL)- Coelenterazine hcp, 90%, 190 times higher luminescence intensity with a faster response time than native coelenterazine | [Molecular Formula]
C25H25N3O2 | [MDL Number]
MFCD03453204 | [MOL File]
123437-32-1.mol | [Molecular Weight]
399.48 |
Chemical Properties | Back Directory | [Melting point ]
>200℃ | [storage temp. ]
-20°C | [solubility ]
Soluble in ethanol, methanol | [form ]
solid | [color ]
Yellow | [λmax]
433nm | [Biological Applications]
Calcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system |
Hazard Information | Back Directory | [Uses]
Coelenterazine hcp has been used:
- as a component of coelenterazine reagent in the reporter assay
- in the purification of Renilla luciferase-labeled Annexin V
- in evaluating the activity of aequorin in Escherichia coli
| [General Description]
Coelenterazine hcp is a semisynthetic analog of coelenterazine. | [Biochem/physiol Actions]
Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine. | [storage]
-20°C |
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