Identification | More | [Name]
2,4-Difluoroaniline | [CAS]
367-25-9 | [Synonyms]
1-amino-2,4-difluorobenzene 2,4-DIFLUOROBENZENAMINE 2,4-DIFLUOROPHENYLAMINE AKOS 91127 LABOTEST-BB LTBB000653 2,4-difluoro-anilin Aniline, 2,4-difluoro- Benzenamine, 2,4-difluoro- Difluoroaniline 2,4-DIFLUROANILINE 2,4-Difluorobenzeneamine 2,4-Difluoroaniline,99% 2,4-Difluoroaniline97% 2,4-DIFLOUROANILINE 2,4-Difluoranilin 2,4-difluoro-benzenamin 2,4-DIFLUOROANILINE 99.5% 4,6-Difluorophenylamine | [EINECS(EC#)]
206-687-5 | [Molecular Formula]
C6H5F2N | [MDL Number]
MFCD00007648 | [Molecular Weight]
129.11 | [MOL File]
367-25-9.mol |
Chemical Properties | Back Directory | [Appearance]
dark red liquid | [Melting point ]
-7.5 °C (lit.) | [Boiling point ]
170 °C/753 mmHg (lit.) | [density ]
1.268 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.506(lit.)
| [Fp ]
145 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Not miscible or difficult to mix. | [form ]
Liquid | [pka]
3.26±0.10(Predicted) | [color ]
Clear brown | [Specific Gravity]
1.284 (20/4℃) | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. | [Water Solubility ]
1-5 g/100 mL at 20.55 ºC | [Merck ]
14,3147 | [BRN ]
2802556 | [CAS DataBase Reference]
367-25-9(CAS DataBase Reference) | [NIST Chemistry Reference]
2,4-Difluoroaniline(367-25-9) | [EPA Substance Registry System]
2,4-Difluoroaniline (367-25-9) |
Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [RIDADR ]
UN 2941 6.1/PG 3
| [WGK Germany ]
1
| [RTECS ]
BX3680000
| [F ]
8-9-23 | [Hazard Note ]
Toxic | [TSCA ]
T | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214210 |
Raw materials And Preparation Products | Back Directory | [Raw materials]
Iron-->Potassium fluoride-->1,3-Dichlorobenzene-->m-Phenylenediamine-->2,4-Difluoronitrobenzene | [Preparation Products]
TOSUFLOXACIN TOSILATE-->TEMAFLOXACIN-->Diflufenican-->Diflunisal-->2,4,5-Trifluorobenzoic acid-->N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine-->2-Bromo-4,6-difluorophenol-->2,4-DIFLUORO-6-NITROANILINE-->2-AMINO-4,6-DIFLUOROBENZOTHIAZOLE-->Benzamide, 5-chloro-N-(2,4-difluorophenyl)-2-hydroxy--->1H-Pyrrole-3-carboxaldehyde, 1-(2,4-difluorophenyl)-2,5-dimethyl--->1-(2,4-DIFLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE-->N-(2,4-DIFLUOROPHENYL)MALEAMIC ACID-->benzyl 2,4-difluoro-3-forMylphenylcarbaMate-->Acetamide, N-(2,4-difluorophenyl)-2-(hydroxyimino)- |
Hazard Information | Back Directory | [General Description]
Dark reddish-purple liquid. | [Reactivity Profile]
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. | [Air & Water Reactions]
This chemical may be sensitive to prolonged exposure to air. . Water soluble. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: This compound may be irritating to tissues. | [Fire Hazard]
This compound is combustible. | [Chemical Properties]
dark red liquid | [Uses]
2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields. |
Questions And Answer | Back Directory | [Description]
2,4-difluoroaniline is an important intermediate used in organic synthesis, pharmaceuticals agrochemicals, dyes, and agricultural chemicals.
| [Reference]
R. Garth Pews, J. A. Gall, Process and intermediates for the preparation of 2,6-difluoroaniline, Paten US5041674A
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