| Identification | More | [Name]
2-Fluoroaniline | [CAS]
348-54-9 | [Synonyms]
1-AMINO-2-FLUOROBENZENE
2-FLUOROANILINE
AKOS 91139
AKOS BBS-00003628
FLUOROANILINE-2
LABOTEST-BB LTBB000714
O-FLUOROANILINE
1,2-fluorobenzenamine
2-fluoro-benzenamin
2-Fluorobenzenamine
2-fluoro-Benzenamine
2-Fluoro-phenylamine
Aniline, 2-fluoro-
Aniline, o-fluoro-
2-Fluoroaniline o-Fluoroaniline
2-FLUOROANILINE, 99+%
2-FluoroanilineForSynthesis
2-Fluoroaniline99.5%
Benzenamine, 2-fluoro-
2-Fluoranilin | [EINECS(EC#)]
206-478-9 | [Molecular Formula]
C6H6FN | [MDL Number]
MFCD00007642 | [Molecular Weight]
111.12 | [MOL File]
348-54-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to brown liquid | [Melting point ]
-29 °C | [Boiling point ]
182-183 °C(lit.)
| [density ]
1.151 g/mL at 25 °C(lit.)
| [vapor pressure ]
1 hPa (20 °C) | [refractive index ]
n20/D 1.544(lit.)
| [Fp ]
140 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
17g/l | [form ]
Liquid | [pka]
3.2(at 25℃) | [color ]
Clear colorless | [Specific Gravity]
1.151 | [Water Solubility ]
17 g/L (20°C) | [Detection Methods]
GC,NMR | [BRN ]
1524219 | [CAS DataBase Reference]
348-54-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzenamine, 2-fluoro-(348-54-9) | [EPA Substance Registry System]
348-54-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/38:Irritating to eyes and skin .
R33:Danger of cumulative effects.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . | [RIDADR ]
UN 2941 6.1/PG 3
| [WGK Germany ]
2
| [RTECS ]
BY1390000 | [Autoignition Temperature]
600 °C | [Hazard Note ]
Toxic/Irritant | [TSCA ]
T | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214210 |
| Hazard Information | Back Directory | [General Description]
Clear liquid with a mild sweet odor. Sinks in and mixes slowly with water. | [Reactivity Profile]
2-FLUOROANILINE(348-54-9) is a base. Neutralizes acids to form salts plus water in an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. | [Air & Water Reactions]
Water soluble. | [Health Hazard]
Inhalation or ingestion causes bluish tint to fingernails, lips and ears indicative of cyanosis; headache, drowsiness, and nausea, followed by unconsciousness. Liquid can be absorbed through skin and cause similar symptoms. Contact with eyes causes irritation. | [Fire Hazard]
Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires. | [Chemical Properties]
Clear colorless to brown liquid | [Uses]
2-Fluoroaniline (cas# 348-54-9) is a useful reagent for the synthesis of insecticides. | [Application]
2-Fluoroaniline can be used to synthesize thermosensitive dye FH-102, which is a black thermosensitive dye with wide application and excellent performance. The dye can be used in the production of terminal output printing paper of electronic computer, EEG recording paper, telephone fax paper and transparent thermal film for oil field. | [Definition]
ChEBI: A derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate | [Synthesis Reference(s)]
Tetrahedron Letters, 25, p. 3415, 1984 DOI: 10.1016/S0040-4039(01)91034-2 | [Metabolic pathway]
2-Fluoro and 3-fluoroanilines are preferentially
hydroxylated at the para-position, and 4-fluoroaniline is
both p- and o-hydroxylated to a significant extent by
rat liver microsomes and is not accompanied with an
NIH shift to give 4-hydroxyl-3-fluoroaniline. |
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