| Identification | Back Directory | [Name]
CEFATHIAMIDINE | [CAS]
33075-00-2 | [Synonyms]
CEFATHIAMIDINE
CEFATHIAMIDINE USP/EP/BP
Cefathiamidine Impurity B
7-[α-[(N,N'-Diisopropylamidino)thio]acetylamino]cephalosporanic acid
7-(alpha-((n,n'-diisopropylamidino)thio)acetylamino)cephalosporanic acid
5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(2-((n,n'-diisopropyla
7-(2-((n,n'-diisopropylamidino)thio)acetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic aci acetate
(6R)-3-[(Acetyloxy)methyl]-7α-[2-[(N,N'-diisopropylamidino)thio]acetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-3-(acetoxymethyl)-7-(2-(((E)-N,N'-diisopropylcarbamimidoyl)thio)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
(6R,7R)-3-(acetyloxymethyl)-7-[[2-[N,N'-di(propan-2-yl)carbamimidoyl]sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[2-[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-, (6R,7R)- | [EINECS(EC#)]
278-355-8 | [Molecular Formula]
C19H28N4O6S2 | [MDL Number]
MFCD01682011 | [MOL File]
33075-00-2.mol | [Molecular Weight]
472.58 |
| Chemical Properties | Back Directory | [Melting point ]
>140°C (dec.) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.67±0.50(Predicted) | [color ]
White to Off-White | [Stability:]
Unstable in Solution |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Cefathiamidine is an antibacterial agent that exhibits a broad spectrum of bactericidal activity against gram-positive bacteria. | [Definition]
ChEBI: Cefathiamidine is a cephalosporin. | [in vivo]
Cefathiamidine is not absorbed orally and is, thus, administered through the parenteral route (intravenously or intramuscularly). Cefathiamidine is widely distributed in most bodily fluids and tissues; however, Cefathiamidine cannot pass through the blood-brain barrier. The protein-binding capacity of Cefathiamidine is 23%, and more than 90% of Cefathiamidine is excreted unchanged by the kidney[1]. | [IC 50]
β-lactam |
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