| Identification | More | [Name]
N-Methyl-N-(trimethylsilyl)trifluoroacetamide | [CAS]
24589-78-4 | [Synonyms]
2,2,2-TRIFLUORO-N-METHYL-N-(TRIMETHYLSILYL)-ACETAMIDE
MSTFA
MSTFA ACTIVATED I
MSTFA ACTIVATED II
MSTFA ACTIVATED III
N-METHYL-N-TMS-TRIFLUOROACETAMIDE
N-METHYL-N-(TRIMETHYLSILYL)-2,2,2-TRIFLUOROACETAMIDE
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED I
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED II
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED III
N-METHYLTRIMETHYLSILYLTRIFLUORACETAMIDE
N-METHYLTRIMETHYLSILYLTRIFLUOROACETAMIDE
N-TRIMETHYLSILYL-N-METHYL TRIFLUOROACETAMIDE
2,2,2-trifluoro-n-methyl-n-(trimethylsilyl)-acetamid
N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE W. 1% TMCS
N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO-ACE TAMIDE, DERIVATIZATION GRADE
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACET-A MIDE, FOR GC
N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAM, 10x1ML PACKSIZE
N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE 98% | [EINECS(EC#)]
246-331-6 | [Molecular Formula]
C6H12F3NOSi | [MDL Number]
MFCD00000411 | [Molecular Weight]
199.25 | [MOL File]
24589-78-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to light yellow liquid | [Melting point ]
98-100°C | [Boiling point ]
130132°C
| [density ]
1.075 g/mL at 25 °C(lit.)
| [vapor density ]
>1 (vs air)
| [vapor pressure ]
8.8 mm Hg ( 27 °C)
| [refractive index ]
n20/D 1.383
| [Fp ]
77 °F
| [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Liquid | [pka]
-1.34±0.70(Predicted) | [color ]
Clear colorless to light yellow | [Specific Gravity]
1.076 | [Water Solubility ]
reacts | [Hydrolytic Sensitivity]
7: reacts slowly with moisture/water | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC | [BRN ]
1941550 | [InChIKey]
MSPCIZMDDUQPGJ-UHFFFAOYSA-N | [CAS DataBase Reference]
24589-78-4(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive;Store under inert gas | [EPA Substance Registry System]
24589-78-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [RTECS ]
AC9800000
| [F ]
10-21 | [Hazard Note ]
Flammable | [TSCA ]
T | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to light yellow liquid | [Uses]
A new metabolite of Famprofazone in humans. | [Uses]
pharmaceutical intermediate | [Definition]
ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat
sation agent used in gas chromatography/mass spectrometry applications. | [General Description]
N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane. | [reaction suitability]
reagent type: derivatization reagent
reaction type: Silylations | [Purification Methods]
Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.] |
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