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ChemicalBook--->CAS DataBase List--->2183473-16-5

2183473-16-5

2183473-16-5 Structure

2183473-16-5 Structure
IdentificationBack Directory
[Name]

BDP FL-PEG4-(4E)-TCO
[CAS]

2183473-16-5
[Synonyms]

BDP FL-PEG4-TCO
BDP FL-PEG4-(4E)-TCO
[Molecular Formula]

C33H49BF2N4O7
[MDL Number]

MFCD31580132
[MOL File]

2183473-16-5.mol
[Molecular Weight]

662.57
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF, DCM, low solubility in water
Hazard InformationBack Directory
[Description]

BDP FL-PEG4-TCO is a BDP FL linker containing a TCO group and a hydrophilic PEG spacer arm. The TCO group allows site-specific conjugation by Click Chemistry and is ideal for conjugation with of antibodies, proteins or probes. The hydrophilic PEG spacer arm can increase water solubility.
[Uses]

BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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