| Identification | More | [Name]
N'-Nitro-L-arginine | [CAS]
2149-70-4 | [Synonyms]
ARGININE(NO2)-OH
ARG(NO2)
H-ARG(NO2)-OH
H-ARG(NO2)-OME
H-L-ARG(NO2)-OH
L-ARGININE(NITRO)
L-NA
L-NG-NITROARGININE
L-NITROARGININE
L-NNA
L-NO2ARG
L-NOARG
N5-[IMINO(NITROAMINO)METHYL]-L-ORNITHINE
N5-[NITROAMIDINO]-L-2,5-DIAMINOPENTANOIC ACID
NG-NITRO-L-ARGININE
NG-NO2-L-ARG
NITRO-L-ARGININE
N-NITRO-L-ARGININE
N-OMEGA-NITRO-L-ARGININE
S(+)-N5-[IMINO(NITROAMINO)METHYL]-ORNITHINE | [EINECS(EC#)]
218-418-9 | [Molecular Formula]
C6H13N5O4 | [MDL Number]
MFCD00007033 | [Molecular Weight]
219.2 | [MOL File]
2149-70-4.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO OFF-WHITE POWDER | [Melting point ]
257 °C (dec.)(lit.)
| [alpha ]
23.5 º (c=4, 2N HCl 24 ºC) | [Boiling point ]
360°C (rough estimate) | [density ]
1.4177 (rough estimate) | [refractive index ]
1.8000 (estimate) | [RTECS ]
RM2982100 | [storage temp. ]
Store at RT. | [solubility ]
DMF: <50 μg/ml; DMSO: <50 μg/ml; Ethanol: <50 μg/ml; PBS pH 7.2: 1 mg/ml | [form ]
powder to crystal | [pka]
2.49±0.24(Predicted) | [color ]
White to Almost white | [Water Solubility ]
Soluble to 5 mM in water | [BRN ]
1728914 | [InChIKey]
MRAUNPAHJZDYCK-BYPYZUCNSA-N | [CAS DataBase Reference]
2149-70-4(CAS DataBase Reference) | [EPA Substance Registry System]
2149-70-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29299090 |
| Hazard Information | Back Directory | [Hazard]
A reproductive hazard. | [Chemical Properties]
WHITE TO OFF-WHITE POWDER | [Uses]
Nω-Nitro-L-arginine is an inhibitor for nitric oxide synthase and is used in the study of bacterium to determine effective treatments. Used in the study of MRSA (Methicillin-Resistant Staphylococcus Aureus). | [Definition]
ChEBI: N(gamma)-nitro-L-arginine is an L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group. It is a L-arginine derivative, a N-nitro compound, a member of guanidines and a non-proteinogenic L-alpha-amino acid. | [Biological Activity]
NO synthase inhibitor. | [Biochem/physiol Actions]
Nω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia. | [Safety Profile]
Experimental reproductiveeffects. When heated to decomposition it emits toxicvapors of NOx. |
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