| Identification | More | [Name]
2-Amino-5-guanidinovaleric acid monohydrochloride | [CAS]
1119-34-2 | [Synonyms]
2-amino-5-guanidinovaleric acid monohydrochloride
ARG, HCL
ARGININE HYDROCHLORIDE
H-ARG-OH HCL
H-L-ARG-OH HCL
L-2-AMINO-5-GUANIDINOVALERIC ACID HYDROCHLORIDE
L-2-AMINO-5-GUANIDINOVALERIC ACID MONOHYDROCHLORIDE
L-ARG HCL
L-ARGININE HCL
L(+)-ARGININE HYDROCHLORIDE
L-ARGININE HYDROCHLORIDE
L-ARGININE HYDROCHLORIDE SALT
L-(+)-ARGININE MONOHYDROCHLORIDE
L-ARGININE MONOHYDROCHLORIDE
S-(+)-2-AMINO-5-[(AMINOIMINOMETHYL)AMINO]PENTANOIC ACID MONOHYDROCHLORIDE
(S)-(+)-ARGININE HYDROCHLORIDE
argininemonohydrochloride
argivene
detoxargin
hydrochloride,l-arginin | [EINECS(EC#)]
214-275-1 | [Molecular Formula]
C6H15ClN4O2 | [MDL Number]
MFCD00064550 | [Molecular Weight]
210.66 | [MOL File]
1119-34-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
226-230 °C(lit.)
| [alpha ]
22 º (c=8,6N HCl) | [Boiling point ]
235℃[at 101 325 Pa] | [density ]
1.42
| [vapor pressure ]
<1 Pa (20 °C) | [FEMA ]
3819 | [storage temp. ]
2-8°C
| [solubility ]
H2O: 100 mg/mL
| [form ]
powder
| [pka]
1[at 20 ℃] | [color ]
white | [Odor]
odorless | [PH]
5.5-7.0 (25℃, 1M in H2O) | [PH Range]
5.5 - 7 | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [optical activity]
[α]20/D +22.0±0.5°, c = 5% in 5 M HCl | [Water Solubility ]
Soluble in water. Slightly soluble in hot alcohol. | [Sensitive ]
Hygroscopic | [λmax]
λ: 260 nm Amax: ≤0.2
λ: 280 nm Amax: ≤0.1 | [Detection Methods]
T,NMR | [Merck ]
14,780 | [BRN ]
3631658 | [LogP]
-8.5--3.24 at 25℃ | [CAS DataBase Reference]
1119-34-2(CAS DataBase Reference) | [EPA Substance Registry System]
1119-34-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R37:Irritating to the respiratory system.
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [RTECS ]
CF1995500
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
29252000 | [Safety Profile]
Moderately toxic by
intraperitoneal route. Mildly toxic by
ingestion. An experimental teratogen. When
heated to decomposition it emits very toxic
fumes of NOx and HCl. | [Toxicity]
LD50 orally in Rabbit: 12000 mg/kg |
| Hazard Information | Back Directory | [Description]
L-Arginine hydrochloride (1119-34-2) is a salt form of L-Arginine, where hydrochloric acid is added to enhance stability and solubility. Arginine hydrochloride is a L-alpha-amino acid. An essential amino acid that is physiologically active in the L-form. L-Arginine might be effective at lowering blood pressure, reducing the symptoms of angina and PAD , and treating erectile dysfunction due to a physical cause.
| [Chemical Properties]
White crystalline powder | [Uses]
An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function). | [Uses]
gastric acid depressant | [Definition]
ChEBI: Arginine hydrochloride is a L-alpha-amino acid. | [Brand name]
R-Gene 10 (Pharmacia & Upjohn). | [General Description]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com. | [Biochem/physiol Actions]
L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity. | [Side effects]
L-arginine has some potential side effects to consider when taking it as a supplement. Some of the more common and benign side effects can include:
nausea, diarrhea, bloating, and abdominal pain. However, L-arginine may result in some serious complications. | [Purification Methods]
A likely impurity is ornithine. Crystallise the salt from H2O at pH 5-7, by adding EtOH to 80% (v/v). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 2649.] |
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