| Identification | More | [Name]
TRIMETHYLSILYL BROMOACETATE | [CAS]
18291-80-0 | [Synonyms]
BROMOACETIC ACID TRIMETHYLSILYL ESTER
TRIMETHYLSILYL BROMOACETATE
Acetic acid, bromo-, trimethylsilyl ester
Trimethylsilyl bromoacetate, 98+%
2-Bromoacetic acid trimethylsilyl ester | [EINECS(EC#)]
242-165-3 | [Molecular Formula]
C5H11BrO2Si | [MDL Number]
MFCD00000187 | [Molecular Weight]
211.13 | [MOL File]
18291-80-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear slightly yellow liquid | [Boiling point ]
57-58 °C/9 mmHg (lit.) | [density ]
1.284 g/mL at 25 °C(lit.)
| [vapor density ]
>1 (vs air)
| [refractive index ]
n20/D 1.442(lit.)
| [Fp ]
83 °F
| [storage temp. ]
Flammables area | [Specific Gravity]
1.299 | [Hydrolytic Sensitivity]
7: reacts slowly with moisture/water | [Sensitive ]
Moisture Sensitive | [BRN ]
1927560 | [CAS DataBase Reference]
18291-80-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R10:Flammable.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2920 8/PG 2
| [WGK Germany ]
3
| [F ]
10-19-21 | [TSCA ]
No | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29310099 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear slightly yellow liquid | [Uses]
Trimethylsilyl bromoacetate has been used:
- in the preparation of new imidazolium salts functionalized with the trimethylsilyl ester group
- as alkylating agent in the synthesis of succinate fragment of pantocin B (antibiotic natural product)
- in the synthesis of taxol derivatives tethered at C2′ and C-7 to glutamate and folate
|
|
|