| Identification | More | [Name]
L-Lysine hydrochloride | [CAS]
657-27-2 | [Synonyms]
2,6-DIAMINOHEXANOIC ACID HYDROCHLORIDE
H-L-LYS-OH HCL
H-LYS-OH HCL
L(+)-2,6-DIAMINOCAPROIC ACID, HYDROCHLORIDE
L(+)-2,6-DIAMINOHEXANOIC ACID, HYDROCHLORIDE
L-(+)-2,6-DIAMINO-N-CAPROIC ACID MONOHYDROCHLORIDE
L-LYS HCL
L(+)-LYS HYDROCHLORIDE
L-LYSINE HCL
L(+)-LYSINE HYDROCHLORIDE
L-LYSINE HYDROCHLORIDE
L-LYSINE HYDROCHLORIDE SALT
L-(+)-LYSINE MONOHYDROCHLORIDE
L-LYSINE MONOHYDROCHLORIDE
LYS, HCL
LYSINE HCL
LYSINE HCL, L-
LYSINE HYDROCHLORIDE
LYSINE-L HCL
LYSINE MONOHYDROCHLORIDE | [EINECS(EC#)]
211-519-9 | [Molecular Formula]
C6H15ClN2O2 | [MDL Number]
MFCD00064564 | [Molecular Weight]
182.65 | [MOL File]
657-27-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
263 °C (dec.)(lit.)
| [alpha ]
21 º (c=8, 6N HCl) | [density ]
1.28 g/cm3 (20℃) | [vapor pressure ]
<1 Pa (20 °C) | [FEMA ]
3847 | [storage temp. ]
2-8°C
| [solubility ]
H2O: 100 mg/mL
| [form ]
powder
| [color ]
White to Off-white | [Odor]
odorless | [PH]
5.5-6.0 (100g/l, H2O, 20℃) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [optical activity]
[α]20/D +20.5±0.5°, c = 5% in 5 M HCl | [Water Solubility ]
65 g/100 mL (20 ºC) | [λmax]
λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1 | [Detection Methods]
T | [Merck ]
14,5636 | [BRN ]
3563889 | [LogP]
-1.036 (est) | [CAS DataBase Reference]
657-27-2(CAS DataBase Reference) | [EPA Substance Registry System]
657-27-2(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid. |
| Safety Data | Back Directory | [Hazard Codes ]
| [Risk Statements ]
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 1789 8/PG 3
| [WGK Germany ]
2 | [RTECS ]
OL5650000
| [F ]
10 | [HS Code ]
29224100 | [Safety Profile]
iWdly toxic by
ingestion. When heated to decomposition it
emits very toxic fumes of HCl and NOx. |
| Hazard Information | Back Directory | [Description]
A white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble
in alcohol and in ether. It melts at about 260°C with decomposition. | [Chemical Properties]
White crystalline powder | [Uses]
amino acid, nutrient | [Uses]
L-(+)-Lysine Monohydrochloride | [Definition]
ChEBI: The hydrochloride salt of L-lysine | [General Description]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com. | [Biochem/physiol Actions]
L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections. | [Side effects]
L-Lysine hydrochloride may cause side effects such as stomach pain and diarrhea.
| [Purification Methods]
Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.] |
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