Identification | More | [Name]
Clodinafop-propargyl | [CAS]
105512-06-9 | [Synonyms]
cga-184927 CLODINAFOP-PROPARGYL CLODINAFOP-PROPARGYL ESTER propynyl (r)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy] phenoxy]propanoate Topik CLODINAFOP-PROPARGYL PESTANAL Propanoic acid, 2-4-(5-chloro-3-fluoro-2-pyridinyl)oxyphenoxy-, 2-propynyl ester, (2R)- clodinafop-propargyl ester (bsi, pa e-iso) Clodinafopacid (R)-2-[4-[(5-Chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propionic acid 2-propynyl ester Prop-2-ynyl (2R)-2-[4-(5-chloro-3-fluoropyridin-2-yl)oxyphenoxy]propanoate | [Molecular Formula]
C17H13ClFNO4 | [MDL Number]
MFCD01632328 | [Molecular Weight]
349.74 | [MOL File]
105512-06-9.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn;N,N,Xn | [Risk Statements ]
R20/22:Harmful by inhalation and if swallowed . R43:May cause sensitization by skin contact. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves . S60:This material and/or its container must be disposed of as hazardous waste . S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 2811 | [WGK Germany ]
3 | [HS Code ]
29333990 | [Hazardous Substances Data]
105512-06-9(Hazardous Substances Data) | [Toxicity]
LD50 in rats (mg/kg): 1829 orally; >2000 dermally; LC50 in rats (4 hr): >2325 mg/m3 by inhalation (Amrein) |
Hazard Information | Back Directory | [Description]
Clodinafop-propargyl is a foliar-absorbed aryloxyphenoxypropionate herbicide which has the capacity to inhibit the lipid biosynthesizing enzyme, acetyl coenzyme-A-carboxylase. Clodinafop-propargyl is a member of the Oxyphenoxy acid ester chemical class, which includes the active ingredients fluazifop-butyl, fenoxaprop-ethyl, diclofop methyl, quizalofop-ethyl and haloxyfop-methyl. | [Chemical Properties]
Pure Clodinafop-propargyl is colorless crystal, vapor pressure (25℃)3.19×10-3mPa, Solubility (25℃): water 4.0mg/L, ethyl alcohol 97 mg/L, acetone 880 mg/L, methyl benzene 690mg/L, n-hexane 0.0086 mg/L. Distribution coefficient (octane/water): KOWlogP=3.9(25℃). Clodinafop-propargyl can inhibit the synthesis of ester-like biology. It can be used to control amur foxtail, oat grass, avena sterilis, green bristlegrass and other weeds. | [Uses]
Herbicide. | [Uses]
Herbicides for weed control in wheat. | [Definition]
ChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of clodinafop with the hydroxy group of prop-2-yn-1-ol. It is widely used as a herbicide for the control of annual grass weeds in cereal crops. | [Mode of action]
Clodinafop-propargyl is to inhibit the activity of acetyl-CoA carboxylase in plants. It is a systemic conductive herbicide, absorbed by the leaves and sheaths of plants, transmitted by phloem, and accumulated in meristems of plants. In this case, acetyl-CoA carboxylase is inhibited, and fatty acid synthesis is stopped. So cell growth and division cannot proceed normally, and lipid-containing structures such as membrane systems are destroyed, leading to plant death. | [Toxicity evaluation]
a) Mammalian toxicity : WHO Classification : Class III slightly hazardous” b) Environmental toxicity : It is non-toxic to fish, birds and bees. Shelf life :Two years under normal storage conditions (Tech grade and Formulation) |
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