tert-Butyl carbazate synthesis
- Product Name:tert-Butyl carbazate
- CAS Number:870-46-2
- Molecular formula:C5H12N2O2
- Molecular Weight:132.16
24424-99-5
839 suppliers
$13.50/25G
870-46-2
545 suppliers
$5.00/10g
Yield:870-46-2 97%
Reaction Conditions:
with hydrazine hydrate in isopropyl alcohol at 0; for 2 h;
Steps:
Preparation of tert-butyl hydrazinecarboxylate 10:
Hydrazine hydrate (113 mg, 2.26 mmol, 2.26 equiv) was dissolved in IPA (5 mL) and cooled down to 0 °C. Di-tert-butyl carbonate (174 mg, 1 mmol, 1 equiv) in IPA (1 mL) was added drop-wise and the mixture was stirred for 2 h. The solvent was then evaporated and the residue was dissolved in DCM, dried over MgSO4, and filtered. Evaporation of the solvent gave tert-butyl hydrazinecarboxylate 10 as a white semi-solid (128 mg, 97%). 1H NMR (300 MHz, CDCl3) δ 6.73(s, 1H), 3.83 (s, 2H), 1.46 (s, 9H); 13C NMR (75 MHz, CDCl3) δ 158.2, 80.1, 28.2.21
References:
Vertesaljai, Peter;Lebedyeva, Iryna O.;Oliferenko, Alexander A.;Qi, Xin;Fu, Junjie;Ostrov, David A.;Asiri, Abdullah M.;Dennis Hall;Katritzky, Alan [Tetrahedron Letters,2015,vol. 56,# 48,p. 6653 - 6655]
6627-89-0
145 suppliers
$8.00/5g
870-46-2
545 suppliers
$5.00/10g
1860-21-5
1 suppliers
inquiry
870-46-2
545 suppliers
$5.00/10g
29518-83-0
2 suppliers
inquiry
870-46-2
545 suppliers
$5.00/10g
99969-78-5
0 suppliers
inquiry
870-46-2
545 suppliers
$5.00/10g