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ChemicalBook CAS DataBase List Sodium dodecyl sulfate
151-21-3

Sodium dodecyl sulfate synthesis

4synthesis methods
Sodium lauryl sulfate is prepared by sulfation of lauryl alcohol, followed by neutralization with sodium carbonate.
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Yield:151-21-3 451 g

Reaction Conditions:

Stage #1: tris(dodecyloxy)boranewith sulfuric acid in 1,2-dichloro-ethane;Cooling with ice;
Stage #2: with sodium hydroxide in methanol;1,2-dichloro-ethane; for 0.5 h;Cooling with ice;

Steps:

3 Example 3

The solid boron ester dissolves in 300mL dichloroethane and a homogenous mixture is acquired. While tridodecyl borate in the reactor transferred into an ice-bathe is being stirred with a mechanical mixer, 150 g H2SO4(98%) is added dropwise. Precipitated boric acid is filtered through a sintered glass funnel and thefiltered liquid is transferred to 2L volume Erlenemeyer flask cooled in ice-bath. Concentrated methanol solution comprising60g NaOH solution previously prepared is added dropwise for 30 minutes on boron ester stirred vigorously. Precipitation of sodium dodecyl sulfate is observed clearly during this addition. When the product is filtered, milky white obtainedsolids are washed with cold methanol solution and dried for 3 hours at 50°C under vacuum. 451 g product is yielded quantitatively. H-NMR spectrum of the product re-crystallized from ethanol represents exactly the spectrum of the sodiumdodecyl sulfate (SDS) in the literature.

References:

EP2851362,2015,A1 Location in patent:Paragraph 0036

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