Sodium 3-methyl-2-oxobutanoate synthesis
- Product Name:Sodium 3-methyl-2-oxobutanoate
- CAS Number:3715-29-5
- Molecular formula:C5H7NaO3
- Molecular Weight:138.1
7526-77-4
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3715-29-5
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Yield:3715-29-5 92.85%
Reaction Conditions:
with sodium ethanolate in butan-1-ol at 40; under 600.06 Torr; for 2 h;Solvent;Temperature;Pressure;
Steps:
4.2; 5.2 (2) Preparation of α-ketovaline salt
Add 27.9g of sodium ethoxide (0.410mol) and 9.60g of isopropylidene hydantoin (0.0686mol) to 50mL of butanol; the temperature is raised to 40°C under slight negative pressure (pressure is -0.08MPa), and the reaction time is 2 hours; another container holds water for collecting the ammonia gas produced to prepare ammonia water; after the reaction is completed, the temperature is lowered, and the temperature of the reaction solution is controlled to be 10 ° C, incubated for 2 hours, filtered, and dried to obtain 8.79 g of sodium ketovaline. . The yield is 92.85%, and the purity is more than 99.91%.
References:
CN113735775,2021,A Location in patent:Paragraph 0038; 0041
20201-24-5
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3715-29-5
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1068-55-9
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95-92-1
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3715-29-5
137 suppliers
$17.00/250mg