ChemicalBook CAS DataBase List Pyridine sulfur trioxide

Pyridine sulfur trioxide synthesis

4synthesis methods

Product Name:Pyridine sulfur trioxide
CAS Number:26412-87-3
Molecular formula:C5H5NO3S
Molecular Weight:159.16

110-86-1 Synthesis

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26412-87-3
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Yield:-

Reaction Conditions:

with chlorosulfonic acid in dichloromethane at 0; for 0.5 h;Inert atmosphere;

Steps:

Procedure for synthesis of SO .Py

[0302] To a solution of pyridine (4 mL) in DCM (20 mL) at 0C, chlorosulfonic acid (1.6 mL) was added dropwise and the mixture stirred for 30 min. The reaction mixture was then filtered and the precipitate was washed with ice cold water (3 × 20 mL), ice cold sat. NaHCO (2 × 10 mL), ice cold water (2 × 10 mL) (till the pH of the filtrate was 7), cold 3 (0551) EtOH (2 × 20 mL), cold toluene (10 mL) and cold DCM (10 mL). The precipitated SO .Py (0552) 3 was then thoroughly dried under high vacuum and used within 24 h.

References:

WO2018/68090,2018,A1 Location in patent:Paragraph 0187; 0302

110-86-1 Synthesis

110-86-1
852 suppliers
$9.00/5g