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ChemicalBook CAS DataBase List Propanil
709-98-8

Propanil synthesis

6synthesis methods
-

Yield:709-98-8 88%

Reaction Conditions:

with iron(III) chloride;chlorine in N,N-dimethyl-formamide at 70; for 3 h;Temperature;

Steps:

1
Under stirring,Adding N-(4-chlorophenyl)propanamide (0.1 mol),N,N-dimethylformamide (50 ml) and iron trichloride (0.01 mol),Slowly warm up to 70 ° C,Passing chlorine gas to react,The tail gas produced by the reaction is absorbed by 30% liquid alkali.After 3 hr, TLC detected complete reaction.Stop the reaction,Add 100 ml of deionized water to the reaction solution.Stirring,Filtered to give a white solid.Melting point 91~92°C,The yield was 88% based on N-(4-chlorophenyl)propanamide (0.1 mol).The purity of HPLC was 98.9%.The solid obtained is the enemy.

References:

Shandong Runbo Biological Technology Co., Ltd.;Sun Guoqing;Hou Yongsheng;Song Jian CN108752229, 2018, A Location in patent:Paragraph 0021; 0025; 0029; 0037

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