N-(TERT-BUTOXYCARBONYL)-L-ALANINE-1-13C synthesis
- Product Name:N-(TERT-BUTOXYCARBONYL)-L-ALANINE-1-13C
- CAS Number:201740-78-5
- Molecular formula:C8H15NO4
- Molecular Weight:190.22
24424-99-5
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$13.50/25G
21764-56-7
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$110.00/100mg
201740-78-5
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$45.00/10mg
Yield:201740-78-5 97%
Reaction Conditions:
Stage #1: di-tert-butyl dicarbonate;<1-13C>-L-alaninewith sodium hydrogencarbonate;sodium hydroxide in 1,4-dioxane at 20; for 28 h;
Stage #2: with dmap in 1,4-dioxane;water at 50; for 1 h;
References:
Hata, Ryunosuke;Nonaka, Hiroshi;Takakusagi, Yoichi;Ichikawa, Kazuhiro;Sando, Shinsuke [Angewandte Chemie - International Edition,2016,vol. 55,# 5,p. 1765 - 1768][Angew. Chem.,2016,vol. 128,# 5,p. 1797 - 1800,4] Location in patent:supporting information