Levetiracetam acid synthesis
- Product Name:Levetiracetam acid
- CAS Number:103833-72-3
- Molecular formula:C8H13NO3
- Molecular Weight:171.19
67118-31-4
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 0.33 h / 0 °C
1.2: 25 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 16 h / -78 °C
2.1: 141 mg / LiOH*H2O; H2O2 / tetrahydrofuran / 7 h / 0 °C
References:
Boschi, Francesca;Camps, Pelayo;Comes-Franchini, Mauro;Munoz-Torrero, Diego;Ricci, Alfredo;Sanchez, Laura [Tetrahedron Asymmetry,2005,vol. 16,# 22,p. 3739 - 3745]