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ChemicalBook CAS DataBase List Hydroxytetracaine
490-98-2

Hydroxytetracaine synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: Na2CO3; NaI; ethanol
2: aq.-ethanolic Na2CO3
3: SOCl2; pyridine; benzene / anschliessendes Behandeln mit 2-Dimethylamino-aethanol
4: palladium/charcoal; aq.-ethanolic HCl / Hydrogenation
5: zinc-powder; acetic acid; benzene

References:

Clinton et al. [Journal of the American Chemical Society,1951,vol. 73,p. 3674,3678]

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