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ChemicalBook CAS DataBase List Diuron
330-54-1

Diuron synthesis

8synthesis methods
-

Yield:330-54-1 98.3%

Reaction Conditions:

in toluene at 5 - 12;Inert atmosphere;Green chemistry;Temperature;

Steps:

1 Example 1

Four bottles of 100 grams of toluene, cooled to about 5 , access to 6.5g dimethylamine gas, the formation of dimethylamine toluene solution (mass concentration of 6.1%).With stirring, 100 g of a toluene solution of 3,4-dichloroisocyanate in toluene at 25%3,4-dichloroisocyanate and dimethylamine feed molar ratio of 1: 1.08) into the nitrogen 2h (detection of acidity 0.1% or less), in 30-50min drop into the dimethylamine solution, Make sure that the dropping process temperature is between 5-12 ° C and after dripping. Continue stirring for 30 min. Filtration (filter cake can be washed with all the mother liquor) to a white solid, 90 after drying the quality of 30.5g, impurity content of 0.1%, the yield of 98.3%.After the preparation of the mother liquor, the synthesis yield was 98.2% and the impurity content was 0.11%.

References:

CN107129445,2017,A Location in patent:Paragraph 0010; 0027; 0028; 0029; 0030; 0031; 0032

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