Benzoic acid, 3-(phenylmethoxy)-, methyl ester synthesis

9synthesis methods

Product Name:Benzoic acid, 3-(phenylmethoxy)-, methyl ester
CAS Number:79678-37-8
Molecular formula:C15H14O3
Molecular Weight:242.27

19438-10-9 Synthesis

19438-10-9
246 suppliers
$6.00/5g

100-44-7 Synthesis

100-44-7
642 suppliers
$13.50/250G

Benzoic acid, 3-(phenylmethoxy)-, methyl ester

79678-37-8
28 suppliers
$148.00/5g

Yield:79678-37-8 98.8%

Reaction Conditions:

with potassium carbonate;potassium iodide in acetone at 20; for 24 h;

Steps:

3

3,5-Diamino-6-Benzyloxyphenyl-1,2,4-triazine compounds - Procedure [31 ; Reaction scheme:; Methyl 3 - benzyloxybenzoate [3]; A mixture of methyl 3-hydroxybenzoate [Aldrich] (15.2g; O.I Omol), benzyl chloride (12.7g; O.IOmol), potassium carbonate (13.8g; O.IOmol), potassium iodide (1.Og) and acetone (150cm³) was stirred at room temperature until no benzyl chloride remained (~24hrs).The mixture was then poured slowly into stirred crushed ice/water (200cm³) and the precipitated solid filtered off. The product was washed with cold water until neutral and dried in vacuo at 45° to give the title compound as a colourless powder.Yield = 23.9g (98.8%)Mpt = 77 - 78°

References:

WO2009/90431,2009,A1 Location in patent:Page/Page column 32-33

19438-10-9 Synthesis

19438-10-9
246 suppliers
$6.00/5g